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Copy Number

The number of molecules of a particular type on or in a cell or part of a cell. Usually applied to specific genes or to plasmids within a bacterium… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
MeDIP real‐time qPCR of maternal peripheral blood reliably identifies trisomy 21
To reevaluate the efficiency of the 12 differentially methylated regions (DMRs) used in the methylated DNA immunoprecipitation… 
2010
2010
Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes.
Highly Cited
2007
Highly Cited
2007
Genetic and epigenetic alterations in the differential diagnosis of malignant melanoma and spitzoid lesion
Background  The histopathological differentiation of malignant melanoma and Spitz naevus often presents diagnostic problems. 
Highly Cited
2005
Highly Cited
2005
Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors.
Highly Cited
2000
Highly Cited
2000
Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.
Highly Cited
1997
Highly Cited
1997
Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma.
Comparative genomic hybridization (CGH) analyses were performed on 27 human pleural mesothelioma tumour specimens, consisting of… 
Highly Cited
1991
Highly Cited
1991
Centromeric copy number of chromosome 7 is strongly correlated with tumor grade and labeling index in human bladder cancer.
The relationship between interphase cytogenetics and tumor grade, stage, and proliferative activity was investigated in 27… 
Highly Cited
1988
Highly Cited
1988
Persistence and replication of plasmid DNA microinjected into early embryos of Xenopus laevis.
Highly Cited
1987
Highly Cited
1987
A human papilloma virus type 11 transcript encoding an E1--E4 protein.
Highly Cited
1980
Highly Cited
1980
Control of Plasmid R1 Replication: Functions Involved in Replication, Copy Number Control, Incompatibility, and Switch-off of Replication
A small derivative of plasmid R1 was used to integratively suppress a chromosomal dnaA(Ts) mutation. The strain obtained grew… 
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