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Copy Number

The number of molecules of a particular type on or in a cell or part of a cell. Usually applied to specific genes or to plasmids within a bacterium… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Genetic and epigenetic alterations in the differential diagnosis of malignant melanoma and spitzoid lesion
Background  The histopathological differentiation of malignant melanoma and Spitz naevus often presents diagnostic problems. 
Highly Cited
2005
Highly Cited
2005
Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors.
2002
2002
Chromosomal imbalances detected by comparative genomic hybridization are associated with outcome of patients with hepatocellular carcinoma
Biologic characteristics of tumors are greatly affected by genetic aberrations. However, to the authors' knowledge there is no… 
Highly Cited
2000
Highly Cited
2000
Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines.
Highly Cited
1998
Highly Cited
1998
Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.
We previously isolated a novel 4.7-kb RS447 sequence, which tandemly repeated approximately 50-70 copies and resided on human… 
Highly Cited
1998
Highly Cited
1998
Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung.
The differential diagnosis of mesothelioma, primary adenocarcinomas and pleural metastases frequently causes problems. We have… 
Highly Cited
1991
Highly Cited
1991
Detection of numerical chromosome aberrations using in situ hybridization in paraffin sections of routinely processed bladder cancers.
Highly Cited
1991
Highly Cited
1991
Centromeric copy number of chromosome 7 is strongly correlated with tumor grade and labeling index in human bladder cancer.
The relationship between interphase cytogenetics and tumor grade, stage, and proliferative activity was investigated in 27… 
Highly Cited
1987
Highly Cited
1987
A human papilloma virus type 11 transcript encoding an E1--E4 protein.
Highly Cited
1980
Highly Cited
1980
Control of Plasmid R1 Replication: Functions Involved in Replication, Copy Number Control, Incompatibility, and Switch-off of Replication
A small derivative of plasmid R1 was used to integratively suppress a chromosomal dnaA(Ts) mutation. The strain obtained grew… 
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