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Copper Chelation

Copper Chelation involves non-covalent coordination bonding between copper and an organic chemical, often as part of an enzyme.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Significance We demonstrate that glutathione biosynthesis is controlled by hypoxia-inducible factor 1 and is critical for… Expand
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Highly Cited
2015
Highly Cited
2015
Abstract Aims: Several neurodegenerative disorders show alterations in glutamatergic synapses and increased susceptibility to… Expand
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Highly Cited
2013
Highly Cited
2013
Significance This paper describes the mechanism by which copper mediates the interplay between the two energy-producing pathways… Expand
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Highly Cited
2011
Highly Cited
2011
Metal overload plays an important role in several diseases or intoxications, like in Wilson's disease, a major genetic disorder… Expand
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Review
2006
Review
2006
Copper stimulates the proliferation and migration of endothelial cells and is required for the secretion of several angiogenic… Expand
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Highly Cited
2006
Highly Cited
2006
Copper, though essential, is potentially toxic heavy metal at supraoptimal level and has widespread contamination. The present… Expand
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Highly Cited
2004
Highly Cited
2004
There is now direct evidence that copper is bound to amyloid-beta peptide (Abeta) in senile plaque of Alzheimer's disease. Copper… Expand
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Highly Cited
2004
Highly Cited
2004
The key protein in Alzheimer's disease, the amyloid precursor protein (APP), is a ubiquitously expressed copper-binding… Expand
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Highly Cited
2002
Highly Cited
2002
Flavonoids are well known as effective free radical scavengers exhibiting therefore an antioxidant behaviour. Another antioxidant… Expand
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Highly Cited
2000
Highly Cited
2000
The Atx1 metallochaperone protein is a cytoplasmic Cu(I) receptor that functions in intracellular copper trafficking pathways in… Expand
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