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A majority of US women report past use of vaginal lubricants to enhance the ease and comfort of intimate sexual… Expand ABSTRACT Clinical trials evaluating the efficacy of nonoxynol-9 (N-9) as a topical microbicide concluded that N-9 offers no in… Expand OBJECTIVES
To evaluate symptoms and signs of genital irritation, vaginal leakage and acceptability of polystyrene sulfonate (PSS… Expand Background Efforts to develop topical microbicide products have all but ignored evaluation for rectal use. Goal The goal of this… Expand Vaginally applied gels offer a promising approach for preventing unwanted pregnancies and sexually transmitted infections… Expand The rheological properties of 4 commercially available contraceptive drug delivery gels and their dilutions with a vaginal fluid… Expand To evaluate the effects of nonoxynol-9 (N-9) on the vaginal flora and epithelium, 48 women (16 in each group) were evaluated by… Expand The objective of this study was to compare the tolerability of Advantage 24 to two other spermicides containing non-oxynol-9 (N-9… Expand We evaluated the ability of the widely used spermicide nonoxynol-9, Conceptrol gel containing nonoxynol-9, and Conceptrol vehicle… Expand The in vitro activity of nonoxynol-9 against four serotypes (C, D, H, and K) of Chlamydia trachomatis was investigated. A… Expand