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Compound Kushen Injection

Known as: CKI, Yanshu Injection 
A traditional Chinese medicine (TCM) formulation composed of compound Kushen injection (CKI) containing aqueous extracts from the roots of Kushen… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
  • P. Ingham
  • Cold Spring Harbor perspectives in biology
  • 2012
  • Corpus ID: 13098190
The Hedgehog (Hh) proteins belong to one of a small number of families of secreted signals that play a central role in the… Expand
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Highly Cited
2010
Highly Cited
2010
Mdm2 is the major negative regulator of the p53 pathway. Here, we report that Mdm2 is rapidly degraded after DNA damage and that… Expand
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Highly Cited
2008
Highly Cited
2008
Primary cilia are microtubule-based organelles involved in signal transduction and project from the surface of most vertebrate… Expand
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Highly Cited
2006
Highly Cited
2006
p27kip1, a cyclin-dependent kinase (CDK) inhibitor (CKI), generally suppresses CDK activity in proliferating cells. Although… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Recent studies have shown that casein kinase I ε (CKIε) is an essential regulator of the mammalian circadian clock… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Contact inhibition has been implicated as an important antiproliferative mechanism in developing and mature corneal… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The cyclin-dependent kinase inhibitors (CKIs) have different patterns of expression in vascular diseases. The Kip/Cip… Expand
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Highly Cited
1997
Highly Cited
1997
The human DNA repair protein apurinic/apyrimidinic endonuclease (APE) is a dual-function protein that has important roles in both… Expand
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Highly Cited
1996
Highly Cited
1996
In eukaryotic cells, the coordinated activation of different cyclin-dependent kinases regulates entry into S-phase. In vitro and… Expand
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Highly Cited
1995
Highly Cited
1995
Cyclin-dependent kinases (Cdks) are positive regulators of cell proliferation, whereas Cdk inhibitors (CKIs) inhibit… Expand
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