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Complement component C6

Known as: Complement 6, Complement, C6, C6, Complement 
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (2)

C6 Deficiency, SubtotalComplement Component 6 Deficiency

Broader (2)

C6 geneImmunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Close linkage between mouse genes determining the two forms of complement component C6 and component C7, and cis action of a C6 Regulatory Gene
Two forms of mouse complement component C6, with molecular weights (Mrs) of 90 and 100 kilodaltons (kd), are present in the sera… 
Review
2000
Review
2000
Molecular mechanisms of complement component C6 deficiency; a hypervariable exon 6 region responsible for three of six reported defects
The complement proteins, C5 through C9, together comprise the terminal complement components; on activation these combine to form… 
1998
1998
Prolonged discordant xenograft survival by inhibition of the intrinsic coagulation pathway in complement C6-deficient recipients.
BACKGROUND Xenotransplantation of vascularized organs between unmodified discordant species results in hyperacute graft rejection… 
1995
1995
DNA polymorphisms of the complement C6 and C7 genes
The linked C6 and C7 loci are rich in genetic markers, both at the protein and DNA levels. There are now seven common DNA… 
1995
1995
Complement component C6 and C7 haplotypes associated with deficiencies of C6
Both complete C6‐deficiency (C6*Q0) and subtotal C6‐deficiency (C6*SD) have been described as simple recessive traits and C6*SD… 
1993
1993
Polymorphism of human complement component C6: an amino acid substitution (Glu/Ala) within the second thrombospondin repeat differentiates between the two common allotypes C6 A and C6 B.
Component C6 of the human complement system exhibits a genetic polymorphism in all populations tested so far. Using isoelectric… 
1991
1991
MspI polymorphism at the human complement component C6 gene (C6)
as •• «B2 Two RFLPs at the D12S51 locus R.Newton, D.J.Henderson, D.J.Cockburn, Y.Boyd and G.E.Moore Action Research Laboratory… 
Highly Cited
1989
Highly Cited
1989
Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
Complement C6 is one of five plasma proteins that are incorporated into the lytic terminal complement complex on lipid membranes… 
Highly Cited
1989
Highly Cited
1989
The molecular architecture of human complement component C6.
1983
1983
POLYMORPHISM OF THE COMPLEMENT COMPONENT C6 IN JAPANESE
Genetic polymorphism of human C6 was investigated in Japanese using isoelectric focusing and a specific haemolytic overlay method… 
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