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Complement component C6

Known as: Complement 6, Complement, C6, C6, Complement 
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Background: The membrane attack complex (MAC) is an ancient component of immune defense that assembles lytic pores in pathogen… Expand
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2004
2004
Complement component C6 is a part of the lytic membrane attack complex formed during complement activation. Animal modeling to… Expand
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1999
1999
In order to elucidate the function of complement component C6, truncated C6 molecules were expressed recombinantly. These were… Expand
1996
1996
Deficiency of the sixth component of complement (C6D) is frequently associated with recurrent neisserial infections, especially… Expand
1995
1995
The linked C6 and C7 loci are rich in genetic markers, both at the protein and DNA levels. There are now seven common DNA… Expand
1993
1993
Component C6 of the human complement system exhibits a genetic polymorphism in all populations tested so far. Using isoelectric… Expand
Highly Cited
1989
Highly Cited
1989
The role of the lytic complement C5b-9 membrane attack complex (MAC) in acute passive transfer experimental autoimmune myasthenia… Expand
Highly Cited
1989
Highly Cited
1989
The molecular architecture of human complement component C6 was elucidated at several levels of structural organization. The… Expand
Highly Cited
1989
Highly Cited
1989
Complement C6 is one of five plasma proteins that are incorporated into the lytic terminal complement complex on lipid membranes… Expand
1983
1983
Genetic polymorphism of human C6 was investigated in Japanese using isoelectric focusing and a specific haemolytic overlay method… Expand