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Complement component C6
Known as:
Complement 6
, Complement, C6
, C6, Complement
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A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32…
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National Institutes of Health
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Related topics
Related topics
11 relations
Narrower (2)
C6 Deficiency, Subtotal
Complement Component 6 Deficiency
Broader (2)
C6 gene
Immunologic Factors
Process of secretion
agonists
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Nucleotide Sequence Analyses of Human Complement 6 (C6) Gene Suggest Balancing Selection
M. Soejima
,
H. Tachida
,
M. Tsuneoka
,
O. Takenaka
,
H. Kimura
,
Y. Koda
Annals of Human Genetics
2005
Corpus ID: 12512821
The sixth complement component (C6) has a common charge polymorphism, C6A and C6B, with similar gene frequencies in all major…
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2004
2004
Close linkage between mouse genes determining the two forms of complement component C6 and component C7, and cis action of a C6 Regulatory Gene
A. Orren
,
M. Hobart
,
H. Raynor Nash
,
P. Lachmann
Immunogenetics
2004
Corpus ID: 23141674
Two forms of mouse complement component C6, with molecular weights (Mrs) of 90 and 100 kilodaltons (kd), are present in the sera…
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1998
1998
Prolonged discordant xenograft survival by inhibition of the intrinsic coagulation pathway in complement C6-deficient recipients.
F. Jakobs
,
E. Davis
,
T. White
,
F. Sanfilippo
,
W. Baldwin
The Journal of Heart and Lung Transplantation
1998
Corpus ID: 36113754
BACKGROUND Xenotransplantation of vascularized organs between unmodified discordant species results in hyperacute graft rejection…
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1995
1995
DNA polymorphisms of the complement C6 and C7 genes
B. Fernie
,
R. Würzner
,
D. J. Unsworth
,
R. Tuxworth
,
M. Hobart
Annals of Human Genetics
1995
Corpus ID: 41065156
The linked C6 and C7 loci are rich in genetic markers, both at the protein and DNA levels. There are now seven common DNA…
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1995
1995
Complement component C6 and C7 haplotypes associated with deficiencies of C6
B. Fernie
,
A. Orren
,
+4 authors
M. Hobart
Annals of Human Genetics
1995
Corpus ID: 25722634
Both complete C6‐deficiency (C6*Q0) and subtotal C6‐deficiency (C6*SD) have been described as simple recessive traits and C6*SD…
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1993
1993
Polymorphism of human complement component C6: an amino acid substitution (Glu/Ala) within the second thrombospondin repeat differentiates between the two common allotypes C6 A and C6 B.
G. Dewald
,
M. Nöthen
,
S. Cichon
Biochemical and Biophysical Research…
1993
Corpus ID: 13477849
Component C6 of the human complement system exhibits a genetic polymorphism in all populations tested so far. Using isoelectric…
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1991
1991
MspI polymorphism at the human complement component C6 gene (C6)
E. Coto
,
O. Dominguez
,
E. Martínez-Naves
,
F. Setién
,
V. Gutierrez
,
C. López-Larrea
Nucleic Acids Res.
1991
Corpus ID: 205222960
as •• «B2 Two RFLPs at the D12S51 locus R.Newton, D.J.Henderson, D.J.Cockburn, Y.Boyd and G.E.Moore Action Research Laboratory…
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Highly Cited
1989
Highly Cited
1989
Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
J. Haefliger
,
J. Tschopp
,
N. Vial
,
D. Jenne
Journal of Biological Chemistry
1989
Corpus ID: 26914278
Complement C6 is one of five plasma proteins that are incorporated into the lytic terminal complement complex on lipid membranes…
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Highly Cited
1989
Highly Cited
1989
The molecular architecture of human complement component C6.
R. Discipio
,
T. Hugli
Journal of Biological Chemistry
1989
Corpus ID: 35288427
1983
1983
POLYMORPHISM OF THE COMPLEMENT COMPONENT C6 IN JAPANESE
K. Tokunaga
,
Y. Yukiyma
,
K. Omoto
European journal of immunogenetics
1983
Corpus ID: 27021412
Genetic polymorphism of human C6 was investigated in Japanese using isoelectric focusing and a specific haemolytic overlay method…
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