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Complement component C6

Known as: Complement 6, Complement, C6, C6, Complement 
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (2)

C6 Deficiency, SubtotalComplement Component 6 Deficiency

Broader (2)

C6 geneImmunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects
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Papers overview

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2012
2012
Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC).
The complement membrane attack complex (MAC) is formed by the sequential assembly of C5b with four homologous proteins as follows… Expand
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2004
2004
Molecular basis for complement component 6 (C6) deficiency in rats and mice.
Complement component C6 is a part of the lytic membrane attack complex formed during complement activation. Animal modeling to… Expand
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1998
1998
Function of the factor I modules (FIMS) of human complement component C6.
In order to elucidate the function of complement component C6, truncated C6 molecules were expressed recombinantly. These were… Expand
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1996
1996
Molecular bases for inherited human complement component C6 deficiency in two unrelated individuals.
Deficiency of the sixth component of complement (C6D) is frequently associated with recurrent neisserial infections, especially… Expand
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1993
1993
A physical map of the human complement component C6, C7, and C9 genes
The genes for human complement components C6, C7, and C9 are linked on chromosome 5. In this report we describe the physical… Expand
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1989
1989
Inhibition of acute passive transfer experimental autoimmune myasthenia gravis with Fab antibody to complement C6.
The role of the lytic complement C5b-9 membrane attack complex (MAC) in acute passive transfer experimental autoimmune myasthenia… Expand
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1989
1989
The molecular architecture of human complement component C6.
The molecular architecture of human complement component C6 was elucidated at several levels of structural organization. The… Expand
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1989
1989
Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
Complement C6 is one of five plasma proteins that are incorporated into the lytic terminal complement complex on lipid membranes… Expand
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1985
1985
Close linkage between mouse genes determining the two forms of complement component C6 and component C7, and cis action of a C6 Regulatory Gene
Two forms of mouse complement component C6, with molecular weights (Mrs) of 90 and 100 kilodaltons (kd), are present in the sera… Expand
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1983
1983
Polymorphism of the complement component C6 in Japanese.
Genetic polymorphism of human C6 was investigated in Japanese using isoelectric focusing and a specific haemolytic overlay method… Expand
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