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Complement component C6

Known as: Complement 6, Complement, C6, C6, Complement 
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (2)

C6 Deficiency, SubtotalComplement Component 6 Deficiency

Broader (2)

C6 geneImmunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2012
Highly Cited
2012
Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)*♦
Background: The membrane attack complex (MAC) is an ancient component of immune defense that assembles lytic pores in pathogen… 
2004
2004
A physical map of the human complement component C6, C7, and C9 genes
The genes for human complement components C6, C7, and C9 are linked on chromosome 5. In this report we describe the physical… 
Review
2000
Review
2000
High prevalence of complement component C6 deficiency among African‐Americans in the South‐eastern USA
Complement component C6 is a part of the membrane attack complex that forms a pore‐like structure in cell membranes following… 
1998
1998
Prolonged discordant xenograft survival by inhibition of the intrinsic coagulation pathway in complement C6-deficient recipients.
BACKGROUND Xenotransplantation of vascularized organs between unmodified discordant species results in hyperacute graft rejection… 
1996
1996
Molecular bases for inherited human complement component C6 deficiency in two unrelated individuals.
Deficiency of the sixth component of complement (C6D) is frequently associated with recurrent neisserial infections, especially… 
1995
1995
DNA polymorphisms of the complement C6 and C7 genes
The linked C6 and C7 loci are rich in genetic markers, both at the protein and DNA levels. There are now seven common DNA… 
Highly Cited
1989
Highly Cited
1989
Inhibition of acute passive transfer experimental autoimmune myasthenia gravis with Fab antibody to complement C6.
The role of the lytic complement C5b-9 membrane attack complex (MAC) in acute passive transfer experimental autoimmune myasthenia… 
Highly Cited
1989
Highly Cited
1989
Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6.
Complement C6 is one of five plasma proteins that are incorporated into the lytic terminal complement complex on lipid membranes… 
1985
1985
C3 and C6 complement types in schizophrenia.
C3 and C6 complement types were studied in schizophrenic patients and controls. The distributions of the three common C3 types (F… 
1983
1983
POLYMORPHISM OF THE COMPLEMENT COMPONENT C6 IN JAPANESE
Genetic polymorphism of human C6 was investigated in Japanese using isoelectric focusing and a specific haemolytic overlay method… 
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