Complement Membrane Attack Complex

Known as: Complement Sc5b-9, C5b-8-poly-C9, Membrane Attack Complex 
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
020406019732017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In response to complement activation, the membrane attack complex (MAC) assembles from fluid-phase proteins to form pores in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
The membrane attack complex of complement (MAC), apart from its classical role of lysing cells, can also trigger a range of non… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Membrane attack is important for mammalian immune defense against invading microorganisms and infected host cells. Proteins of… (More)
Is this relevant?
2004
2004
OBJECTIVE Monosodium urate monohydrate (MSU) crystals promote gouty inflammation that is critically mediated by neutrophil… (More)
Is this relevant?
2003
2003
The complement system consists of >30 proteins that interact in a carefully regulated manner to destroy invading bacteria and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Accumulating evidence suggests that the generation of complement activation products from filtered complement components in urine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1996
1996
Previous studies have demonstrated that most pathologic changes in the antithymocyte serum (ATS) model of mesangioproliferative… (More)
Is this relevant?
1996
1996
  • Hui-Min Su
  • International archives of allergy and immunology
  • 1996
S-protein/vitronectin participates in the regulation of complement-mediated lysis by incorporating into the membrane attack… (More)
Is this relevant?
1992
1992
The human complement system is an important early host defense against infection. Entamoeba histolytica activates the complement… (More)
  • table I
  • figure 1
  • table II
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1986
Highly Cited
1986
We examined the role of the complement system in the pathogenesis of dermatomyositis. Using an antibody against the neoantigens… (More)
Is this relevant?