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Complement Membrane Attack Complex

Known as: Complement Sc5b-9, C5b-8-poly-C9, Membrane Attack Complex 
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Complement System ProteinsImmunologic Factors
Complement component 9Immunologic CytotoxicityProcess of secretionagonists

Narrower (1)

SC5b-9 protein complex

Papers overview

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1991
1991
C3 activation products, C3 containing immune complexes, the terminal complement complex and native C9 in patients with rheumatoid arthritis.
Complement activation products, C9 and C3-containing circulating immune complexes (CIC), were evaluated in plasma and synovial… 
1986
1986
Immunohistochemical analysis of C3 cleavage fragments, factor H, and the C5b-9 terminal complex of complement in de novo membranous glomerulonephritis occurring in patients with renal transplant.
Fifteen renal biopsies from 13 transplanted patients with de novo membranous nephropathy (DNMN) were investigated by… 
1986
1986
Does complement kill E. coli by producing transmural pores?
Three lines of evidence are presented to indicate that C5b-9 kills serum-sensitive E. coli K 12 cells by generating functional… 
1986
1986
Assembly of the membrane attack complex of complement on small unilamellar phospholipid vesicles.
Light-scattering intensity was shown to be a reliable, direct, and quantitative technique for monitoring the assembly of the… 
Review
1985
Review
1985
Membrane damage by channel-forming proteins: staphylococcal alpha-toxin, streptolysin-O and the C5b-9 complement complex.
One mechanism through which cells can be damaged involves insertion of alien proteins into the membrane bilayer and the formation… 
1984
1984
Complement protein C9 labeled with fluorescein isothiocyanate can be used to monitor C9 polymerization and formation of the cytolytic membrane lesion.
Human complement protein C9 was covalently labeled with the fluorescent chromophore fluorescein isothiocyanate (FITC) with only a… 
1981
1981
Effect of agents that produce membrane disorder on lysis of erythrocytes by complement.
To evaluate the effect of membrane lipid acyl-chain packing on the efficiency of cell lysis by complement, we have studied… 
1981
1981
Permeability characteristics of complement-damaged membranes: evaluation of the membrane leak generated by the complement proteins C5b-9.
Permeability characteristics of the membrane lesion generated by the terminal complement proteins are considered in light of… 
1977
1977
Isolation and properties of complement-resistant strains of Escherichia coli K-12
Several strains that were resistant to the bactericidal action of antibody and complement were isolated from Escherichia coli K… 
1975
1975
Isolation and Subunit Composition of the C5b-9 Complex*
In this communication the isolation and dissociation of the complex is reported . It was found that each of the five terminal…