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Complement Membrane Attack Complex

Known as: Complement Sc5b-9, C5b-8-poly-C9, Membrane Attack Complex 
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
In addition to being a component of innate immunity and an ancient defense mechanism against invading pathogens, complement… Expand
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Review
2016
Review
2016
Renal fibrosis is the usual outcome of an excessive accumulation of extracellular matrix (ECM) that frequently occurs in… Expand
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Highly Cited
2016
Highly Cited
2016
In response to complement activation, the membrane attack complex (MAC) assembles from fluid-phase proteins to form pores in… Expand
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Highly Cited
2013
Highly Cited
2013
The membrane attack complex of complement (MAC), apart from its classical role of lysing cells, can also trigger a range of non… Expand
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Review
2007
Review
2007
Microparticles (MP) derived from vascular endothelium or circulating blood cells circulate in the peripheral blood. They… Expand
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Highly Cited
2005
Highly Cited
2005
Choroidal neovascularization (CNV), or choroidal angiogenesis, is the hallmark of age-related macular degeneration and a leading… Expand
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Review
1991
Review
1991
The complement system consists of both plasma and membrane proteins. The former influence the inflammatory response, immune… Expand
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Highly Cited
1988
Highly Cited
1988
We have investigated the composition and function of membrane microparticles released from platelets exposed to the C5b-9… Expand
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Review
1986
Review
1986
Cell-killing mechanisms are essential components of host defense against infectious agents, parasites, and malignant cells. We… Expand
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Highly Cited
1986
Highly Cited
1986
We examined the role of the complement system in the pathogenesis of dermatomyositis. Using an antibody against the neoantigens… Expand
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