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Complement Hemolytic Activity Assay

Known as: CH50, Total Hemolytic Activity Assay, Total Hemolytic Complement 50% 
A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added to antibody-coated ERYTHROCYTES and the percentage of cell… 
National Institutes of Health

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5 relations
Complement MeasurementComplement System ProteinsLaboratory ProceduresSerum

Papers overview

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Highly Cited
1994
Highly Cited
1994
Hereditary C6 deficiency in a strain of PVG/c rats
A chance observation has led to the discovery of a strain of PVG rats (PVG/c−) which are deficient in complement (C) component C6… 
Highly Cited
1994
Highly Cited
1994
Serum complement levels and severity of sepsis.
The activities (C3a, C4a, C5a) and concentrations (CH50, C3, C4, C5) of serum complement were measured to evaluate the… 
Highly Cited
1993
Highly Cited
1993
Differential cytokine regulation of complement C3, C4, and factor B synthesis in human intestinal epithelial cell line, Caco-2.
In the intestinal tract, the local synthesis of C3 and components of both the classical (C4) and alternative (factor B) C… 
Highly Cited
1989
Highly Cited
1989
Immunotoxicity of the semiconductor gallium arsenide in female B6C3F1 mice.
Highly Cited
1988
Highly Cited
1988
Evidence for the presence of autoantibodies to the collagen-like portion of C1q in systemic lupus erythematosus.
We investigated the connection between the C1q solid-phase binding assay (C1q SPBA) and double-stranded DNA antibodies, and… 
Highly Cited
1985
Highly Cited
1985
The value of complement and immune complex determinations in monitoring disease activity in patients with systemic lupus erythematosus.
Serial serum samples from 33 patients with systemic lupus erythematosus were tested for CH50, C3, C4, and circulating immune… 
Highly Cited
1983
Highly Cited
1983
Symptoms and activation of granulocytes and complement with two dialysis membranes.
Complement (C) activation, neutropenia, and mild pulmonary dysfunction attend hemodialysis (HD) with cellophane [for example… 
Highly Cited
1981
Highly Cited
1981
Immune complexes, complement, and anti-DNA in exacerbations of systemic lupus erythematosus (SLE).
The usefulness of serological parameters in assessing clinical exacerbations of SLE was examined. Patients with active renal… 
Highly Cited
1981
Highly Cited
1981
Role of complement in porphyrin-induced photosensitivity.
Addition of porphyrins to sera of guinea pigs in vitro, followed by irradiation with 405 nm light, resulted in dose-dependent… 
Highly Cited
1978
Highly Cited
1978
Intensive Plasma Exchange on the Cell Separator: Effects on Serum Immunoglobulins and Complement Components
Six patients with IgG myeloma and four patients with glomerulonephritis underwent a course of intensive plasma exchange on a… 
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