Colistin

Known as: Colistinum, Colisticin, Polymyxin E 
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
020040060019502016

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Extensively drug-resistant (XDR) Acinetobacter baumannii may cause serious infections in critically ill patients… (More)
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Highly Cited
2011
Highly Cited
2011
With increasing clinical emergence of multidrug-resistant Gram-negative pathogens and the paucity of new agents to combat these… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Colistin, originally abandoned due to high rates of nephrotoxicity, has been recently reintroduced due to activity… (More)
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Highly Cited
2010
Highly Cited
2010
Infections caused by multidrug-resistant (MDR) Gram-negative bacteria represent a major global health problem. Polymyxin… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES The incidence of ventilator-associated pneumonia (VAP) due to multidrug-resistant (MDR) organisms is increasing… (More)
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Highly Cited
2009
Highly Cited
2009
The mechanism of colistin resistance (Col(r)) in Acinetobacter baumannii was studied by selecting in vitro Col(r) derivatives of… (More)
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Highly Cited
2003
Highly Cited
2003
We prospectively evaluated the efficacy and toxicity of intravenously administered colistin in 35 episodes of ventilator… (More)
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Highly Cited
2003
Highly Cited
2003
INTRODUCTION The increasing prevalence of multiresistant Gram-negative strains in intensive care units (ICUs) has recently… (More)
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Highly Cited
1999
Highly Cited
1999
Sixty nosocomial infections caused by Pseudomonas aeruginosa and Acinetobacter baumannii resistant to aminoglycosides… (More)
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