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Coal tar extract

National Institutes of Health

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7 relations
Antipruritic Activity [PE]Coal TarDrug AllergyPhotosensitizing Activity [PE]
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Papers overview

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2015
2015
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the…
FVB/N mice wild-type, heterozygous or null for Cyp 1b1 were used in a two-stage skin tumor study comparing PAH, benzo[a]pyrene… Expand
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2013
2013
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.
Polycyclic aromatic hydrocarbons (PAHs) are present in the environment as complex mixtures with components that have diverse… Expand
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Highly Cited
2012
Highly Cited
2012
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.
The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of… Expand
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Highly Cited
2011
Highly Cited
2011
The role of CYP1A inhibition in the embryotoxic interactions between hypoxia and polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures in zebrafish (Danio rerio)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with elevated concentrations in waters that may… Expand
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2008
2008
Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract.
Polycyclic aromatic hydrocarbon (PAH) DNA adducts have been associated with carcinogenesis, which is accompanied by multiple… Expand
2004
2004
Double‐blind, randomised, multicentre, parallel group study comparing a 1% coal tar preparation (Exorex) with a 5% coal tar preparation (Alphosyl) in chronic plaque psoriasis
BACKGROUND: Exorex lotion is a novel formulation of prepared coal tar indicated for the treatment of psoriasis. OBJECTIVES: To… Expand
Highly Cited
2003
Highly Cited
2003
Determination of polycyclic aromatic hydrocarbons with molecular weight 300 and 302 in environmental-matrix standard reference materials by gas chromatography/mass spectrometry.
An analytical approach based on gas chromatography/ mass spectrometry (GC/MS) is presented for the measurement of polycyclic… Expand
Highly Cited
1988
Highly Cited
1988
Separation and identification of polycyclic aromatic hydrocarbon isomers of molecular weight 302 in complex mixtures.
The determination of dibenzopyrenes and dibenzofluoranthenes (isomers of molecular weight 302) in complex mixtures has received… Expand
1985
1985
Psoriasis treatment with suberythemogenic ultraviolet B radiation and a coal tar extract.
Forty-nine patients with plaque-type psoriasis were enrolled in a randomized prospective trial that compared the efficacy of… Expand
1982
1982
New coal tar extract and coal tar shampoos. Evaluation by epidermal cell DNA synthesis suppression assay.
Coal tar therapy has been used for many years in the treatment of scaling skin diseases, including psoriasis and eczema. Previous… Expand
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