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Clostridium botulinum type A

Known as: Clostridium botulinum A 
Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXINS, TYPE A which is neurotoxic to humans and animals.
National Institutes of Health

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Papers overview

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2007
2007
Variations in expression and release of botulinum neurotoxin in Clostridium botulinum type A strains.
In this study, we characterized the production and release of botulinum neurotoxin during growth of two Clostridium botulinum… 
Highly Cited
2004
Highly Cited
2004
Differentiation of the Gene Clusters Encoding Botulinum Neurotoxin Type A Complexes in Clostridium botulinum Type A, Ab, and A(B) Strains
ABSTRACT We describe a strategy to identify the clusters of genes encoding components of the botulinum toxin type A (boNT/A… 
1999
1999
Identification of DnaJ-like Chaperone in Clostridium botulinum Type A
Clostridium botulinum type A cells, when challenged to elevated temperature (45°C), increased the expression of at least nine… 
Highly Cited
1990
Highly Cited
1990
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene.
A 26-mer oligonucleotide probe was synthesized (based on the determined amino acid sequence of the N-terminus of the Clostridium… 
1986
1986
Production of toxin by Clostridium botulinum type A strains cured by plasmids
Twelve strains of Clostridium botulinum type A and seven strains of Clostridium sporogenes were screened for plasmids by agarose… 
Highly Cited
1986
Highly Cited
1986
TLC immunostaining characterization of Clostridium botulinum type A neurotoxin binding to gangliosides and free fatty acids
Highly Cited
1984
Highly Cited
1984
Detection of Clostridium botulinum type A toxin by enzyme-linked immunosorbent assay with antibodies produced in immunologically tolerant animals
Immunological tolerance is a state of unresponsiveness to foreign substances (antigens) which can develop in human and animal… 
1983
1983
Clostridium botulinum Type A Growth and Toxin Production in Media and Process Cheese Spread
We found that Clostridium botulinum type A grew well and produced toxin in media with a water activity (aw) of 0.972 or 0.965 and… 
1981
1981
Separation of Clostridium botulinum type A derivative toxin into two fragments.
Two fragments with molecular weights of 105,000 (fragment I) and 58,000 (fragment II) were separated chromatographically from… 
1968
1968
Autolytic formation of spheroplasts and autolysis of cell walls in Clostridium botulinum type A.
Cells of Clostridium botulinum type A strain 190 harvested at logarithmic growth phase rapidly autolysed in phosphate buffer and… 
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