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Clostridium botulinum type A

Known as: Clostridium botulinum A 
Subtype of CLOSTRIDIUM BOTULINUM that produces BOTULINUM TOXINS, TYPE A which is neurotoxic to humans and animals.
National Institutes of Health

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2 relations
aspects of radiation effectsphysiological aspects

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Highly Cited
2003
Highly Cited
2003
Inactivation of Clostridium botulinum type A spores by high-pressure processing at elevated temperatures.
The effects of high-pressure treatments at various temperature-time combinations on the inactivation of spores of Clostridium… Expand
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Highly Cited
2003
Highly Cited
2003
Neurotoxin Gene Clusters in Clostridium botulinum Type A Strains: Sequence Comparison and Evolutionary Implications
The nucleotide sequence of the hemagglutinin (ha) genes and the transcriptional regulator botR gene were determined in type A… Expand
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Highly Cited
2001
Highly Cited
2001
Clostridium botulinum type A haemagglutinin-positive progenitor toxin (HA(+)-PTX) binds to oligosaccharides containing Gal beta1-4GlcNAc through one subcomponent of haemagglutinin (HA1).
Haemagglutinin (HA) activity of Clostridium botulinum type A 19S and 16S toxins (HA-positive progenitor toxin; HA(+)-PTX) was… Expand
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Highly Cited
1996
Highly Cited
1996
Molecular composition of Clostridium botulinum type A progenitor toxins.
The molecular composition of progenitor toxins produced by a Clostridium botulinum type A strain (A-NIH) was analyzed. The strain… Expand
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Highly Cited
1996
Highly Cited
1996
Genetic Characterization of Clostridium botulinum Type A Containing Silent Type B Neurotoxin Gene Sequences (*)
A recent study detected genes encoding type B botulinum neurotoxin in some type A strains of Clostridium botulinum that exhibit… Expand
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Highly Cited
1995
Highly Cited
1995
Genome analysis of Clostridium botulinum type A by pulsed-field gel electrophoresis.
Genomic DNA from type A Clostridium botulinum was digested with restriction endonucleases that cut at rare sites, and the large… Expand
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Highly Cited
1990
Highly Cited
1990
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene.
A 26-mer oligonucleotide probe was synthesized (based on the determined amino acid sequence of the N-terminus of the Clostridium… Expand
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Highly Cited
1987
Highly Cited
1987
The effect of sodium chloride and temperature on the rate and extent of growth of Clostridium botulinum type A in pasteurized pork slurry.
A selective medium was used to enumerate Clostridium botulinum growing in the presence of natural spoilage organisms in a model… Expand
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Highly Cited
1975
Highly Cited
1975
Molecular construction of Clostridium botulinum type A toxins.
Two Clostridium botulinum type A toxic fractions, named large (L) and medium (M) toxins, were eluted from Sephadex G-200. Sucrose… Expand
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Highly Cited
1972
Highly Cited
1972
A common subunit structure in Clostridium botulinum type A, B and E toxins.
Tryptic activation of Clostridium botulinum type E progenitor toxin of 147,000 mol. wt. involves cleavage of the molecule into at… Expand
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