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Clopenthixol
Known as:
1-Piperazineethanol, 4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-
, CLOPENTHIXOL, TRANS
, Clopenthixol [Chemical/Ingredient]
A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
National Institutes of Health
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Related topics
Related topics
15 relations
Broader (2)
Antipsychotic Agents
Dopamine Antagonists
Narrower (4)
Cisordinol
Zuclopenthixol
Zuclopenthixol acetate
clopenthixol decanoate
Clopenthixol:MCnc:Pt:Ser/Plas:Qn
Clopenthixol:Mass:Pt:Dose:Qn
In Blood
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis
M. Huhn
,
A. Nikolakopoulou
,
+10 authors
S. Leucht
The Lancet
2019
Corpus ID: 195887231
Review
2017
Review
2017
Sixty Years of Placebo-Controlled Antipsychotic Drug Trials in Acute Schizophrenia: Systematic Review, Bayesian Meta-Analysis, and Meta-Regression of Efficacy Predictors.
S. Leucht
,
C. Leucht
,
+10 authors
John M. Davis
The American journal of psychiatry
2017
Corpus ID: 27256686
OBJECTIVE Antipsychotic drug efficacy may have decreased over recent decades. The authors present a meta-analysis of all placebo…
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Review
2013
Review
2013
Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia.
T. Declercq
,
M. Petrovic
,
+4 authors
T. Christiaens
The Cochrane database of systematic reviews
2013
Corpus ID: 205191319
BACKGROUND Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in dementia, although the literature is…
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Review
2013
Review
2013
Efficacy and effectiveness of depot versus oral antipsychotics in schizophrenia: synthesizing results across different research designs.
N. Kirson
,
P. Weiden
,
+5 authors
B. Wong
The Journal of clinical psychiatry
2013
Corpus ID: 28715999
OBJECTIVE Nonadherence is a major challenge in schizophrenia treatment. While long-acting (depot) antipsychotic medications are…
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Review
2007
Review
2007
Reversal of resistance in microorganisms by help of non-antibiotics.
J. Kristiansen
,
O. Hendricks
,
+5 authors
H. Keyzer
The Journal of antimicrobial chemotherapy
2007
Corpus ID: 18046116
Intracellular efflux pumps have been largely the research focus in multidrug-resistant (MDR) Gram-positive and Gram-negative…
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Highly Cited
2002
Highly Cited
2002
Separation of cis- and trans-isomers of thioxanthene and dibenz[b,e]oxepin derivatives on calixarene- and resorcinarene-bonded high-performance liquid chromatography stationary phases.
T. Sokoliess
,
U. Menyes
,
U. Roth
,
T. Jira
Journal of chromatography. A
2002
Corpus ID: 24421012
1994
1994
QEEG alpha1 changes after a single dose of high-potency neuroleptics as a predictor of short-term response to treatment in schizophrenic patients
S. Galderisi
,
M. Maj
,
A. Mucci
,
P. Bucci
,
D. Kemali
Biological Psychiatry
1994
Corpus ID: 1932870
1993
1993
Serotonergic aspects of acute extrapyramidal syndromes in nonhuman primates
D. Casey
Schizophrenia Research
1993
Corpus ID: 44949443
1981
1981
Binding of [3H]sulpiride to purified rat striatal synaptic membranes
G. Woodruff
,
S. Freedman
Neuroscience
1981
Corpus ID: 36026734
Highly Cited
1973
Highly Cited
1973
The comparative pharmacology of flupenthixol and some reference neuroleptics.
I. M. Nielsen
,
V. Pedersen
,
+4 authors
A. V. Christensen
Acta pharmacologica et toxicologica
1973
Corpus ID: 43308273
: Flupenthixol, a thioxanthene derivative may exist in two isomeric forms, α and β. Flupenthixol contains 45-55 % α-flupenthixol…
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