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Clopenthixol

Known as: 1-Piperazineethanol, 4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-, CLOPENTHIXOL, TRANS, Clopenthixol [Chemical/Ingredient] 
A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
National Institutes of Health

Related topics

Related topics

15 relations

Broader (2)

Antipsychotic AgentsDopamine Antagonists

Narrower (4)

CisordinolZuclopenthixolZuclopenthixol acetateclopenthixol decanoate
Clopenthixol:MCnc:Pt:Ser/Plas:QnClopenthixol:Mass:Pt:Dose:QnIn Bloodagonists
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis
Summary Background Schizophrenia is one of the most common, burdensome, and costly psychiatric disorders in adults worldwide… Expand
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Review
2007
Review
2007
Reversal of resistance in microorganisms by help of non-antibiotics.
Intracellular efflux pumps have been largely the research focus in multidrug-resistant (MDR) Gram-positive and Gram-negative… Expand
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Highly Cited
2002
Highly Cited
2002
Separation of cis- and trans-isomers of thioxanthene and dibenz[b,e]oxepin derivatives on calixarene- and resorcinarene-bonded high-performance liquid chromatography stationary phases.
The chromatographic behavior of six calix[n]arene phases (n=4, 6, 8) and one calix[4]resorcinarene phase is described for the… Expand
1997
1997
Phototoxic properties of neuroleptic drugs.
BACKGROUND Photo-induced eruptions are well-known adverse effects of some neuroleptic drugs, particularly chlorpromazine… Expand
1994
1994
Exorcism-resistant ghost possession treated with clopenthixol.
  • A. Hale, N. Pinninti
  • The British journal of psychiatry : the journal…
  • 1994
    • Corpus ID: 31648718
BACKGROUND An Indian man now in Britain explained his criminal behaviour as episodic ghost possession. Traditional exorcisms… Expand
1986
1986
LC/MS determination of bromazepam, clopenthixol, and reserpine in serum of a non-fatal case of intoxication.
Combined liquid chromatography and mass spectrometry (LC/MS) with a moving belt interface can be used as a rapid method for the… Expand
Highly Cited
1986
Highly Cited
1986
The antibacterial effect of selected phenothiazines and thioxanthenes on slow-growing mycobacteria.
The aim of the present investigation was to illustrate the antibacterial effect of various phenothiazine and thioxanthene… Expand
1983
1983
Dopamine and mania. The effects of trans- and cis-clopenthixol in a double-blind pilot study.
  • W. Nolen
  • Journal of affective disorders
  • 1983
    • Corpus ID: 6844040
Sordinol is composed of the mixture of cis-clopenthixol and trans-clopenthixol. The two isomers do not differ in several… Expand
1978
1978
Cis(Z)‐clopenthixol and clopenthixol (Sordinol®) in chronic psychotic patients: A DOUBLE‐BLIND CLINICAL INVESTIGATION
The clinical effect of cis(Z)‐clopenthixol has been compared with that of clopenthixol, which is a mixture of the… Expand
Highly Cited
1973
Highly Cited
1973
The comparative pharmacology of flupenthixol and some reference neuroleptics.
: Flupenthixol, a thioxanthene derivative may exist in two isomeric forms, α and β. Flupenthixol contains 45-55 % α-flupenthixol… Expand
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