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Clonal Expansion

Multiplication or reproduction by cell division of a population of identical cells descended from a single progenitor. In immunology, may refer to… 
National Institutes of Health

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Cell Maturation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Characteristics of the somatic hypermutation in the Camelus dromedarius T cell receptor gamma (TRG) and delta (TRD) variable domains.
Highly Cited
2011
Highly Cited
2011
A Monomorphic Haplotype of Chromosome Ia Is Associated with Widespread Success in Clonal and Nonclonal Populations of Toxoplasma gondii
ABSTRACT Toxoplasma gondii is a common parasite of animals that also causes a zoonotic infection in humans. Previous studies have… 
2010
2010
Sex allocation in clonal plants: might clonal expansion enhance fitness gains through male function?
The returns on investment in sexual reproduction are described by fitness gain curves and the shapes of these curves affect… 
Review
2003
Review
2003
Stem cells and diversity
Modern hematology began with two technology-based revolutions. First, assays were developed for cells earlier in lineages than… 
Highly Cited
1995
Highly Cited
1995
Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation.
Mouse 3T3-L1 cells differentiate into fat-laden adipocytes in response to a cocktail of adipogenic hormones. This conversion… 
Review
1993
Review
1993
Stem cell renewal and determination during clonal expansion in normal and leukaemic haemopoiesis.
Normal haemopoiesis is a cellular hierarchy headed by pluripotent stem cells capable of both self renewal and, after… 
Highly Cited
1991
Highly Cited
1991
Predominance of nonproductive rearrangements of VH81X gene segments evidences a dependence of B cell clonal maturation on the structure of nascent H chains.
Ig H chain V regions using the VH81X gene segment were PCR amplified from genomic DNA obtained from either splenic B cells or… 
1991
1991
Additive and multiplicative relative risk in the two-stage clonal expansion model of carcinogenesis.
The effects of exposure to two carcinogens are explored within the context of the two-stage clonal expansion model of… 
1989
1989
Cellular senescence involves stochastic processes causing loss of expression of differentiated function genes: visualization by in situ hybridization for steroid 17 alpha-hydroxylase in bovine…
Highly Cited
1988
Highly Cited
1988
Mutational hot spots in Ig V region genes of human follicular lymphomas
The genes coding for the Ig light chains expressed in two cases of human follicular lymphoma were cloned and sequenced. In each… 
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