Clinical Trials, Randomized

Known as: Randomized Clinical Trials, Trials, Randomized Clinical, clinical randomized trials 
A study in which the participants are assigned by chance to separate groups that compare different treatments; neither the researchers nor the… (More)
National Institutes of Health

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Broader (2)

Controlled Clinical Trials, RandomizedRandomized Controlled Trials as Topic
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Papers overview

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Review
2017
Review
2017
Type 2 Diabetes in the Real World: The Elusive Nature of Glycemic Control.
Despite U.S. Food and Drug Administration (FDA) approval of over 40 new treatment options for type 2 diabetes since 2005, the… (More)
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Highly Cited
2010
Highly Cited
2010
Randomized clinical trials with biomarkers: design issues.
Clinical biomarker tests that aid in making treatment decisions will play an important role in achieving personalized medicine… (More)
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Highly Cited
2007
Highly Cited
2007
External validity of clinical trials in acute myocardial infarction.
BACKGROUND Patients enrolled in randomized clinical trials (RCTs) may not reflect those seen in real-life practice. Our goal was… (More)
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Highly Cited
2006
Highly Cited
2006
Effectiveness of tumor necrosis factor inhibitors in rheumatoid arthritis in an observational cohort study: comparison of patients according to their eligibility for major randomized clinical trials.
OBJECTIVE Randomized clinical trials (RCTs) evaluate the efficacy of treatments in selected groups of patients defined by strict… (More)
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Highly Cited
2004
Highly Cited
2004
A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer.
BACKGROUND Small cell lung cancer (SCLC) is a chemotherapy-responsive tumor type but most patients ultimately experience disease… (More)
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Review
2002
Review
2002
Mediators and moderators of treatment effects in randomized clinical trials.
Randomized clinical trials (RCTs) not only are the gold standard for evaluating the efficacy and effectiveness of psychiatric… (More)
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Highly Cited
2002
Highly Cited
2002
Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival.
PURPOSE Implantable intrathecal drug delivery systems (IDDSs) have been used to manage refractory cancer pain, but there are no… (More)
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Highly Cited
2001
Highly Cited
2001
Treatment of reflex sympathetic dystrophy (CRPS type 1): a research synthesis of 21 randomized clinical trials.
A blinded meta analysis was performed on randomized clinical trials (RCT) on the medicinal treatment of reflex sympathetic… (More)
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Highly Cited
2000
Highly Cited
2000
Reasons for accepting or declining to participate in randomized clinical trials for cancer therapy
This paper reports on the reasons why patients agreed to or declined entry into randomized trials of cancer following discussions… (More)
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Highly Cited
1987
Highly Cited
1987
Publication bias and clinical trials.
A study was performed to evaluate the extent to which the medical literature may be misleading as a result of selective… (More)
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