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Chlorpheniramine

Known as: 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine, ?-(4-chlorophenyl)-?-(2-pyridyl)propyldimethylamine, Clorfeniramina 
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications… Expand
National Institutes of Health

Related topics

Related topics

45 relations
12 HR Chlorpheniramine Maleate 12 MG Extended Release Oral Tablet [Chlor-Trimeton]AMMONIUM CHLORIDE/CHLORPHENIRAMINE/CODEINE/PHENYLEPHRINE/POTASSIAcetaminophen 325 MG / Chlorpheniramine Maleate 2 MG / Phenylephrine Hydrochloride 5 MG Oral TabletChlorpheniramine / Ephedrine / Guaifenesin / Phenobarbital / Theophylline
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Narrower (22)

AllergisanAuron-Misheil-TherapyCHLORPHENIRAMINE POLISTIREXChlo-Amine
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Broader (2)

AntihistaminesPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Treatment of Cluster Headache: The American Headache Society Evidence‐Based Guidelines
Cluster headache (CH), the most common trigeminal autonomic cephalalgia, is an extremely debilitating primary headache disorder… Expand
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Highly Cited
2009
Highly Cited
2009
Ruthenium-catalyzed N-alkylation of amines and sulfonamides using borrowing hydrogen methodology.
The alkylation of amines by alcohols has been achieved using 0.5 mol % [Ru(p-cymene)Cl(2)](2) with the bidentate phosphines dppf… Expand
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Highly Cited
2002
Highly Cited
2002
Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets.
Acetaminophen, phenylephrine and chlorpheniramine are frequently associated in pharmaceutical formulations against the common… Expand
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Highly Cited
2000
Highly Cited
2000
Functional neuroimaging of cognition impaired by a classical antihistamine, d‐chlorpheniramine
Antihistamine induced cognitive decline was evaluated using positron emission tomography (PET) measurement of histamine H1… Expand
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Highly Cited
1999
Highly Cited
1999
Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele.
Genetic polymorphisms in the cytochrome P450 (CYP) family are widely known to contribute to interindividual differences in the… Expand
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Highly Cited
1995
Highly Cited
1995
Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine.
We compared the cardiac electrophysiological actions of two types of H1-receptor antagonists--the piperidines, astemizole and… Expand
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Highly Cited
1995
Highly Cited
1995
Substance P‐induced inflammatory responses in guinea‐pig skin: The effect of specific NK1 receptor antagonists and the role of endogenous mediators
1 The sensory neuropeptide substance P (SP), when released from sensory nerves, has been implicated in the development of… Expand
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Highly Cited
1990
Highly Cited
1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares…
We objectively tested the relative antihistaminic effects of cetirizine, 10 mg; terfenadine, 120 mg; terfenadine, 60 mg… Expand
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Highly Cited
1990
Highly Cited
1990
Pharmacokinetics and pharmacodynamics of terfenadine and chlorpheniramine in the elderly.
In a double-blind, randomized, crossover study, the H1-receptor antagonists, terfenadine and chlorpheniramine, were investigated… Expand
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Highly Cited
1987
Highly Cited
1987
Cimetidine and chlorpheniramine in the treatment of chronic idiopathic urticaria: a multi‐centre randomized double‐blind study
One hundred and twenty patients with chronic idiopathic urticaria, who entered a study at five centres (Sheffield, London… Expand
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