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Chlorothiazide

Known as: Chlorothiazid, 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide, Chlorthiazide 
A short-acting, benzothiadiazinesulfonamide derivative and prototypical thiazide diuretic. Chlorothiazide is excreted unchanged by the kidneys.
National Institutes of Health

Related topics

Related topics

28 relations

Broader (2)

Antihypertensive AgentsDiuretics
AnuriaChlorothiazide 500 MG InjectionChlorothiazide 500 MG Injection [Diuril]Chlorothiazide:PrThr:Pt:Ser/Plas:Ord

Narrower (3)

Chlorothiazide sodiumDiurilUroflux

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography.
Highly Cited
2001
Highly Cited
2001
Are certain diuretics also anticonvulsants?
A history of diuretic use has been shown to be protective for first unprovoked seizure in adult patients. Recent animal studies… 
Highly Cited
1999
Highly Cited
1999
Urinary thiamine excretion in the rat: effects of furosemide, other diuretics, and volume load.
Review
1996
Review
1996
The evolution of low-dose diuretic therapy: the lessons from clinical trials.
Highly Cited
1976
Highly Cited
1976
Regression of atherosclerotic stenosing lesions of the renal arteries and spontaneous cure of systemic hypertension through control of hyperlipidemia.
1975
1975
Interrelationship of chlorothiazide and parathyroid hormone: a micropuncture study.
Sodium and calcium are normally reabsorbed in parallel in the renal tubule. Both parathyroid hormone (PTH) and thiazide diuretics… 
Highly Cited
1971
Highly Cited
1971
Mechanisms of renal lithium handling and their relationship to mineralocorticoids: a dissociation between sodium and lithium ions.
1965
1965
EFFECTS OF BENZOTHIADIAZINE DRUGS ON CARBOHYDRATE METABOLISM.
1963
1963
The effect of mercurial diuretics on adenosinetriphosphatase of rabbit kidney in vitro.
Highly Cited
1958
Highly Cited
1958
CHLOROTHIAZIDE (DIURIL) AS A HYPERURICACIDEMIC AGENT
Chlorothiazide (Diuril) has been recently introduced into therapeutics, first, as an effective nonmercurial diuretic 1 and, more… 
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