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Chlorothiazide

Known as: Chlorothiazid, 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide, Chlorthiazide 
A short-acting, benzothiadiazinesulfonamide derivative and prototypical thiazide diuretic. Chlorothiazide is excreted unchanged by the kidneys.
National Institutes of Health

Related topics

Related topics

28 relations

Broader (2)

Antihypertensive AgentsDiuretics
AnuriaChlorothiazide 500 MG InjectionChlorothiazide 500 MG Injection [Diuril]Chlorothiazide:PrThr:Pt:Ser/Plas:Ord

Narrower (3)

Chlorothiazide sodiumDiurilUroflux

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1996
Review
1996
The evolution of low-dose diuretic therapy: the lessons from clinical trials.
1991
1991
Screening for diuretics in human urine by gas chromatography-mass spectrometry with derivatisation by direct extractive alkylation.
1977
1977
Displacement of bilirubin from human albumin by three diuretics.
Highly Cited
1971
Highly Cited
1971
Mechanisms of renal lithium handling and their relationship to mineralocorticoids: a dissociation between sodium and lithium ions.
1965
1965
EFFECTS OF BENZOTHIADIAZINE DRUGS ON CARBOHYDRATE METABOLISM.
1963
1963
The effect of mercurial diuretics on adenosinetriphosphatase of rabbit kidney in vitro.
1959
1959
Relationship between diuretic and antihypertensive effects of chlorothiazide and mercurial diuretics.
Both chlorothiazide and parenteral mercurial diuretics have an antihypertensive as well as a natriuretic action. Previous… 
1959
1959
Some observations on the pharmacology of hydrochlorothiazide.
Highly Cited
1957
Highly Cited
1957
Clinical and Laboratory Observations on Chlorothiazide (Diuril) An Orally Effective Nonmercurial Diuretic Agent
Chlorothiazide* is a compound whose properties make it valuable in cases where it is desirable to increase the elimination of… 
Highly Cited
1957
Highly Cited
1957
New drugs for hypertension, with special reference to chlorothiazide.
SINCE 1950 a virtual revolution has occurred in the use of drugs for the treatment of arterial hypertension. Within this period… 
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