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Chloramphenicol

Known as: Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-, [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, chloramphenicols 
A semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses… 
National Institutes of Health

Related topics

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42 relations

Narrower (25)

1,3-diacetylchloramphenicol3-(bromoacetyl)chloramphenicolCervugidChloramex
Amphenicols [Chemical/Ingredient]Bacterial InfectionsCYP2C19 protein, humanChloramphenicol 0.01 MG/MG Ophthalmic Ointment [Chloromycetin]

Broader (2)

Anti-Bacterial AgentsPropylene Glycols

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China.
Review
2007
Review
2007
Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool.
The dramatic spread of antibiotic resistance is a crisis in the treatment of infectious diseases that affect humans. Several… 
Highly Cited
2003
Highly Cited
2003
Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit.
Highly Cited
1996
Highly Cited
1996
AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants
Multiple-antibiotic-resistance (Mar) mutants of Escherichia coli are resistant to a wide variety of antibiotics, and increased… 
Review
1994
Review
1994
Inactivation of antibiotics and the dissemination of resistance genes.
The emergence of multidrug-resistant bacteria is a phenomenon of concern to the clinician and the pharmaceutical industry, as it… 
Highly Cited
1991
Highly Cited
1991
Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives.
Highly Cited
1988
Highly Cited
1988
A simple phase-extraction assay for chloramphenicol acyltransferase activity.
Highly Cited
1974
Highly Cited
1974
ANTIBIOTIC AND CHEMOTHERAPY
Review
1974
Review
1974
Inhibitors of protein synthesis
Highly Cited
1972
Highly Cited
1972
Nature of Col E1 Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol
The colicinogenic factor E1 (Col E1) in Escherichia coli continues to replicate by a semiconservative mechanism in the presence… 
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