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Chemokine CCL27

Known as: Cutaneous T Cell Attracting Chemokine, Cutaneous T-Cell-Attracting Chemokine, ESkine 
A CC-type chemokine with specificity for CCR10 RECEPTORS. It is constitutively expressed in the skin and may play a role in T-CELL trafficking during… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (3)

CCL27 protein, humanCCL27 wt AlleleCcl27 protein, mouse
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2011
Highly Cited
2011
Kinetics and differential expression of the skin‐related chemokines CCL27 and CCL17 in psoriasis, atopic dermatitis and allergic contact dermatitis
Abstract:  CCL27 and CCL17 are chemokines believed to be involved in the process of establishing the inflammatory infiltrate… 
Highly Cited
2010
Highly Cited
2010
NMR Analysis of the Structure, Dynamics, and Unique Oligomerization Properties of the Chemokine CCL27*
Chemokines have two essential interactions in vivo, with G protein-coupled receptors, which activate intracellular signaling… 
Highly Cited
2007
Highly Cited
2007
Tumor immune escape by the loss of homeostatic chemokine expression
The novel keratinocyte-specific chemokine CCL27 plays a critical role in the organization of skin-associated immune responses by… 
Highly Cited
2005
Highly Cited
2005
Circulating clonal CLA+ and CD4+ T cells in Sézary syndrome express the skin‐homing chemokine receptors CCR4 and CCR10 as well as the lymph node‐homing chemokine receptor CCR7
Background  Adhesion molecules and chemokine receptors are involved in tissue‐specific homing of T cells to the skin and play an… 
Highly Cited
2005
Highly Cited
2005
IL-17 suppresses TNF-alpha-induced CCL27 production through induction of COX-2 in human keratinocytes.
Highly Cited
2004
Highly Cited
2004
Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell- attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic…
2004
2004
Human P-selectin Glycoprotein Ligand-1 (PSGL-1) Interacts with the Skin-associated Chemokine CCL27 via Sulfated Tyrosines at the PSGL-1 Amino Terminus*
P-selectin glycoprotein ligand-1 (PSGL-1), a sialomucin expressed on leukocytes, is a major ligand for P-selectin and mediates… 
2002
2002
The Chemokine ESkine/CCL27 Displays Novel Modes of Intracrine and Paracrine Function1
We have previously shown that the β-chemokine ESkine/CCL27 is differentially spliced to produce two alternative forms. One is a… 
Highly Cited
2000
Highly Cited
2000
Cutting Edge: Identification of the Orphan Receptor G-Protein-Coupled Receptor 2 as CCR10, a Specific Receptor for the Chemokine ESkine1 2
A number of orphan G-protein coupled receptors (GPR) have been reported as putative chemokine receptors. One previously reported… 
1999
1999
ESkine, a Novel β-Chemokine, Is Differentially Spliced to Produce Secretable and Nuclear Targeted Isoforms*
Using the murine embryonal stem cell system, we have identified a novel gene encoding a highly divergent member of the… 
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