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Chemokine CCL22

Known as: Small Inducible Cytokine A22, Chemokine, CCL22, Macrophage-Derived Chemokine 
A CC-type chemokine with specificity for CCR4 RECEPTORS. It has activity towards TH2 CELLS and TC2 CELLS.
National Institutes of Health

Related topics

Related topics

12 relations
CCL22 geneCCL22 wt AlleleIn BloodMacrophage-Derived Chemokine measurement

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CCL22 protein, human

Papers overview

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Highly Cited
2009
Highly Cited
2009
Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome
Netherton syndrome (NS) is a severe genetic skin disease with constant atopic manifestations that is caused by mutations in the… 
Highly Cited
2003
Highly Cited
2003
An Alternatively Spliced Variant of CXCR3 Mediates the Inhibition of Endothelial Cell Growth Induced by IP-10, Mig, and I-TAC, and Acts as Functional Receptor for Platelet Factor 4
The chemokines CXCL9/Mig, CXCL10/IP-10, and CXCL11/I-TAC regulate lymphocyte chemotaxis, mediate vascular pericyte proliferation… 
Highly Cited
2001
Highly Cited
2001
Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells
Chemokines dictate regional trafficking of functionally distinct T cell subsets. In rodents and humans, a unique subset of CD4… 
Highly Cited
2000
Highly Cited
2000
Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.
Highly Cited
1999
Highly Cited
1999
Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine.
Helper T cells are classified into Th1 and Th2 subsets based on their profiles of cytokine production. Th1 cells are involved in… 
Highly Cited
1998
Highly Cited
1998
Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.
Upon exposure to immune or inflammatory stimuli, dendritic cells (DC) migrate from peripheral tissues to lymphoid organs, where… 
Highly Cited
1997
Highly Cited
1997
Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor
Chemokines are a structurally related family of cytokines that are important for leukocyte trafficking. The C-C chemokine… 
Highly Cited
1997
Highly Cited
1997
Impaired Host Defense, Hematopoiesis, Granulomatous Inflammation and Type 1–Type 2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1
CC chemokine receptor 1 (CCR1) is expressed in neutrophils, monocytes, lymphocytes, and eosinophils, and binds the leukocyte… 
Highly Cited
1996
Highly Cited
1996
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes
Several studies have shown that CC chemokines attract T lymphocytes, and that CD45RO+, memory phenotype cells are considered to… 
Review
1995
Review
1995
Interleukin-8 and the chemokine family.
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