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Chemokine CCL20

Known as: Chemokine, SCYA20, Exodus-1 Chemokine, CCL20 Chemokine 
A CC-type chemokine with specificity for CCR6 RECEPTORS. It has activity towards DENDRITIC CELLS; T-LYMPHOCYTES; and B-LYMPHOCYTES.
National Institutes of Health

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CCL20 geneIn BloodProcess of secretionagonists

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CCL20 protein, human

Papers overview

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2017
2017
Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23–dependent murine model
Significance Psoriasis is a chronic skin disease characterized by the infiltration of inflammatory T cells to the skin in… 
Highly Cited
2015
Highly Cited
2015
Tobacco smoke induces production of chemokine CCL20 to promote lung cancer.
Highly Cited
2014
Highly Cited
2014
CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis
Objective Chemokines are known to play an important role in the pathophysiology of alcoholic hepatitis (AH), a form of acute-on… 
2014
2014
CCR6, the Sole Receptor for the Chemokine CCL20, Promotes Spontaneous Intestinal Tumorigenesis
Interactions between the inflammatory chemokine CCL20 and its receptor CCR6 have been associated with colorectal cancer growth… 
2013
2013
Recruitment of CCR6-expressing Th17 cells by CCL20 secreted from plasmin-stimulated macrophages.
In the present study, monocyte-derived human macrophages were differentiated from buffy coats. Naïve CD4⁺ T-cells enriched from… 
Highly Cited
2012
Highly Cited
2012
Lower TCR repertoire diversity in Traj18-deficient mice
2006
2006
Spiral ligament fibrocytes release chemokines in response to otitis media pathogens
Conclusion. Spiral ligament fibrocytes (SLFs) may be involved in the innate immune response of the inner ear by producing… 
Highly Cited
2004
Highly Cited
2004
ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells.
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor belonging to the interferon regulatory factor… 
Highly Cited
2004
Highly Cited
2004
Lymphotoxin beta receptor signaling induces the chemokine CCL20 in intestinal epithelium.
BACKGROUND & AIMS The follicle-associated epithelium (FAE) that overlies Peyer's patches (PPs) exhibits distinct features… 
Highly Cited
2001
Highly Cited
2001
Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/exodus/SCYA20, showing gene structure, splice variants, and chromosome localization.
We describe the genomic organization of a recently identified CC chemokine, MIP3alpha/CCL20 (HGMW-approved symbol SCYA20). The… 
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