Chemogenomics

Known as: Chemical genomics, Chemicogenomics 
Chemogenomics, or chemical genomics, is the systematic screening of targeted chemical libraries of small molecules against individual drug target… (More)
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Highly Cited
2014
Highly Cited
2014
Genome-wide characterization of the in vivo cellular response to perturbation is fundamental to understanding how cells survive… (More)
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Highly Cited
2011
Highly Cited
2011
ChemMine Tools is an online service for small molecule data analysis. It provides a web interface to a set of cheminformatics and… (More)
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Highly Cited
2009
Highly Cited
2009
Recently there has been an explosion of new data sources about genes, proteins, genetic variations, chemical compounds, diseases… (More)
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2009
2009
Chemogenomics is an emerging inter-disciplinary approach to drug discovery that combines traditional ligand-based approaches with… (More)
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Highly Cited
2008
Highly Cited
2008
MOTIVATION Predicting interactions between small molecules and proteins is a crucial step to decipher many biological processes… (More)
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2008
2008
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of… (More)
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Highly Cited
2008
Highly Cited
2008
MOTIVATION Software applications for structural similarity searching and clustering of small molecules play an important role in… (More)
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2007
2007
Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular… (More)
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Highly Cited
2006
Highly Cited
2006
Target identification is a critical step following the discovery of small molecules that elicit a biological phenotype. The… (More)
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2006
2006
Chemogenomics is a new strategy in drug discovery which, in principle, searches for all molecules that are capable of interacting… (More)
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