Chemically-Induced Liver Toxicity

Known as: Toxicity, Chemically-Induced Liver, Chemically-Induced Liver Toxicities, Toxicities, Chemically-Induced Liver 
 
National Institutes of Health

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Broader (1)

Chemical and Drug Induced Liver Injury

Papers overview

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Review
2013
Review
2013
Therapeutic decisions in multiple sclerosis: moving beyond efficacy.
Several innovative disease-modifying treatments (DMTs) for relapsing-remitting multiple sclerosis have been licensed recently or… (More)
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2012
2012
Matrix Metalloproteinase Inhibitor COL-3 Prevents the Development of Paclitaxel-Induced Hyperalgesia in Mice
OBJECTIVE To study the potential of chemically modified tetracycline-3 (COL-3), a potent matrix metalloproteinase (MMP) inhibitor… (More)
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2003
2003
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis.
Sepsis precipitates a systemic inflammatory stimulus that causes systemic release of cytokines and sequestration of… (More)
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2003
2003
Chemically modified tetracyclines induce cytotoxic effects against J774 tumour cell line by activating the apoptotic pathway.
Here, we have studied the effects of chemically modified tetracyclines (CMTs) on apoptosis both at the level of the cytoplasmic… (More)
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2002
2002
Impact of Orthogonal Signal Correction (OSC) on the Predictive Ability of CoMFA Models for the Ciliate Toxicity of Nitrobenzenes
The impact of orthogonal signal correction (OSC) on the prediction power of CoMFA models was studied using a data set of 47… (More)
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2001
2001
Inhibition of tumor cell invasiveness by chemically modified tetracyclines.
COLO 205 is a cell line derived from a human colon carcinoma with high degradative activity towards extracellular matrix (ECM… (More)
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2001
2001
Effects of chemically modified tetracyclines (CMTs) in sensitive, multidrug resistant and apoptosis resistant leukaemia cell lines.
Recently discovered chemically modified tetracyclines (CMTs) have shown in vitro and in vivo anti-proliferative and anti-tumour… (More)
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2000
2000
Down-regulation of trypsinogen-2 expression by chemically modified tetracyclines: association with reduced cancer cell migration.
Many types of human tumor express trypsinogen-2, which may be a significant factor in the activation of pro-MMPs and the… (More)
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Highly Cited
1998
Highly Cited
1998
Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells.
Doxycycline is a commonly used broad-spectrum antibiotic. Recently, it has been shown that it also inhibits the activity of… (More)
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1998
1998
Modulation of nitric oxide production by tetracyclines and chemically modified tetracyclines.
Chemically modified tetracyclines (CMTs) dose-dependently decreased inducible nitric oxide synthase (iNOS) and, consequently… (More)
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