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Cf 1743
Known as:
Cf-1743
, Cf1743
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Pyrimidine Nucleosides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pharmacokinetics and Safety of FV-100, a Novel Oral Anti-Herpes Zoster Nucleoside Analogue, Administered in Single and Multiple Doses to Healthy Young Adult and Elderly Adult Volunteers
H. Pentikis
,
M. Matson
,
+5 authors
Amy N. Morris
Antimicrobial Agents and Chemotherapy
2011
Corpus ID: 26171375
ABSTRACT FV-100 is the prodrug of the highly potent anti-varicella zoster virus bicyclic nucleoside analogue CF-1743. To…
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Review
2010
Review
2010
FV-100: The Most Potent and Selective Anti-Varicella Zoster Virus Agent Reported to Date
Marco Migliore
Antiviral chemistry & chemotherapy
2010
Corpus ID: 19451113
Bicyclic aryl furano pyrimidines represent the most potent anti-varicella zoster virus (VZV) agents reported to date. Lead…
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2010
2010
Evaluation of Novel Phosphoramidate ProTides of the 2′-Fluoro Derivatives of a Potent Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogue
Marco Derudas
,
Maurizio Quintiliani
,
+4 authors
C. Mcguigan
Antiviral chemistry & chemotherapy
2010
Corpus ID: 38644474
Background: Recently, the synthesis and antiviral activity of a series of 2′-fluoro derivatives of the most potent anti-varicella…
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Review
2009
Review
2009
FV100 as a new approach for the possible treatment of varicella-zoster virus infection.
C. Mcguigan
,
J. Balzarini
The Journal of antimicrobial chemotherapy
2009
Corpus ID: 29318149
FV100 is a promising new agent with extreme potency and specificity for varicella-zoster virus (VZV). It is the valyl ester pro…
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2009
2009
A Study of the Safety and Pharmacokinetics of Multiple Ascending Doses of FV-100 in Healthy Subjects
M. Matson
,
H. Pentikis
,
B. Boehlecke
,
E. Wenzel
,
G. Henson
,
A. Morris
2009
Corpus ID: 84902676
Twenty-two of 42 subjects reported at least 1 AEs (Table 2); 23 were thought by the Investigator to be possibly related to study…
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Highly Cited
2007
Highly Cited
2007
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
C. Mcguigan
,
R. Pathirana
,
+13 authors
J. Balzarini
The Journal of antimicrobial chemotherapy
2007
Corpus ID: 40257967
OBJECTIVES To progress the anti-varicella-zoster-virus (VZV) aryl bicyclic nucleoside analogues (BCNAs) to the point of Phase 1…
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