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Cerebral Cavernous Malformations 1

Known as: CCM1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
012320012017

Papers overview

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2015
2015
Cerebral Cavernous Malformation-1 Protein Controls DLL4-Notch3 Signaling Between the Endothelium and Pericytes.
BACKGROUND AND PURPOSE Cerebral cavernous malformation (CCM) is a neurovascular dysplasia characterized by conglomerates of… (More)
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Highly Cited
2012
Highly Cited
2012
Transcriptome-wide changes in Chlamydomonas reinhardtii gene expression regulated by carbon dioxide and the CO2-concentrating mechanism regulator CIA5/CCM1.
We used RNA sequencing to query the Chlamydomonas reinhardtii transcriptome for regulation by CO(2) and by the transcription… (More)
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Highly Cited
2010
Highly Cited
2010
Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling.
Cerebral cavernous malformations (CCM) are frequent vascular abnormalities caused by mutations in one of the CCM genes. CCM1… (More)
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2010
2010
Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype.
Cerebral cavernous malformations (CCM) are vascular lesions causing seizures and stroke. Mutations causing inactivation of one of… (More)
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2006
2006
CCM1 gene deletion identified by MLPA in cerebral cavernous malformation
Familial cerebral cavernous malformations (CCMs) occur with a frequency of 1 in 2000 and may cause recurrent headaches, seizures… (More)
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Highly Cited
2006
Highly Cited
2006
Genotype-phenotype correlations in cerebral cavernous malformations patients.
OBJECTIVE To compare clinical features of CCM1, CCM2, and CCM3 mutation carriers. METHODS A detailed clinical and molecular… (More)
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Highly Cited
2004
Highly Cited
2004
Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.
Hemorrhagic stroke is a significant cause of morbidity and mortality in children, and is frequently associated with intracranial… (More)
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Highly Cited
2004
Highly Cited
2004
The novel Myb transcription factor LCR1 regulates the CO2-responsive gene Cah1, encoding a periplasmic carbonic anhydrase in Chlamydomonas reinhardtii.
Chlamydomonas reinhardtii acclimates to CO2-limiting stress by inducing a set of genes for a carbon-concentrating mechanism (CCM… (More)
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Highly Cited
2001
Highly Cited
2001
Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation.
Cerebral cavernous malformation (CCM) is a common autosomal dominant disorder characterized by venous sinusoids that predispose… (More)
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Highly Cited
2001
Highly Cited
2001
Ccm1, a regulatory gene controlling the induction of a carbon-concentrating mechanism in Chlamydomonas reinhardtii by sensing CO2 availability.
Aquatic photosynthetic organisms, including the green alga Chlamydomonas reinhardtii, induce a set of genes for a carbon… (More)
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