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Central hypothyroidism

Known as: hypothyroidism central, central hypothyroid, Hypothyroidism, central 
Abnormally low levels of thyroid hormones due to a disorder originating within the hypothalamic-pituitary axis.(NICHD)
National Institutes of Health

Related topics

Related topics

9 relations
Endocrine System DiseasesEndocrine systemHYPOTHYROIDISM, CENTRAL, AND TESTICULAR ENLARGEMENTHead and neck structure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Recent advances in central congenital hypothyroidism
Central congenital hypothyroidism (CCH) may occur in isolation, or more frequently in combination with additional pituitary… 
Review
2012
Review
2012
Detection and treatment of congenital hypothyroidism
Congenital hypothyroidism is the most frequent endocrine disorder in neonates. Controversy exists regarding the necessity to… 
Review
2012
Review
2012
Overt and Subclinical Hypothyroidism
Hypothyroidism denotes deficient production of thyroid hormone by the thyroid gland and can be primary (abnormality in thyroid… 
Highly Cited
2007
Highly Cited
2007
Thyroid hormone replacement for central hypothyroidism: a randomized controlled trial comparing two doses of thyroxine (T4) with a combination of T4 and triiodothyronine.
BACKGROUND Dosage of T(4) in central hypothyroidism is primarily guided by the free serum T(4) level (fT4). However, the optimum… 
Review
2007
Review
2007
Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) synthesizing neurons: Role of neuronal afferents and type 2 deiodinase
Highly Cited
2006
Highly Cited
2006
Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patients
Background  The effect of GH replacement on thyroid function in hypopituitary patients has hitherto been studied in small groups… 
Highly Cited
1999
Highly Cited
1999
Central hypothyroidism associated with retinoid X receptor-selective ligands.
BACKGROUND The occurrence of symptomatic central hypothyroidism (characterized by low serum thyrotropin and thyroxine… 
Highly Cited
1999
Highly Cited
1999
Evaluation of the adequacy of levothyroxine replacement therapy in patients with central hypothyroidism.
As there are few data on the evaluation of the adequacy of levothyroxine (L-T4) therapy in patients with central hypothyroidism… 
Highly Cited
1985
Highly Cited
1985
Decreased receptor binding of biologically inactive thyrotropin in central hypothyroidism. Effect of treatment with thyrotropin-releasing hormone.
Previous studies have suggested that certain cases of idiopathic central hypothyroidism of hypothalamic origin may result from… 
Highly Cited
1979
Highly Cited
1979
Thyrotropin secretion in patients with central hypothyroidism: evidence for reduced biological activity of immunoreactive thyrotropin.
TSH concentration was measured in plasma before and after TRH administration (200 micrograms, iv) in 89 patients with documented… 
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