Cavinton
National Institutes of Health
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SummaryThe pharmacokinetics of vinpocetine and its main metabolite, apovincaminic acid (AVA), were studied in the aged…
The alkaloid derivative vinpocetine (14-ethoxycarbonyl-(3α,16α-ethyl)-14,15-eburnamine; Cavinton) has a well known beneficial…
The effects of vinpocetine (Cavinton) on the cerebral glucose metabolism of chronic stroke patients are studied with positron…
Cavinton was introduced into the clinical practice some twenty years ago in Hungary for the treatment of cerebrovascular…
The pharmacokinetics of vinpocetine after 10 mg po and iv doses was studied in six beagle dogs treated in cross-over design. The…
Starting from (+) vincamine (I), simple derivatives of vincaminic acid (II), apovincaminic acid (V) and apovincaminol (VII) were…
Systemic and cerebral haemodynamic effects of ethyl apovincaminate (RGH-4405, Cavinton), a new compound, have been investigated…