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Castration

Known as: Castrations, Surgical Castration, castration surgical 
Surgical removal of the testicles (orchiectomy) or ovaries (oophorectomy) to stop the production of sex hormones. Decreasing the levels of hormones… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
BACKGROUND Poly ADP-ribose polymerase (PARP) inhibitors, such as olaparib, are being explored as a treatment option for… Expand
Review
2019
Review
2019
BACKGROUND Darolutamide is a structurally unique androgen‐receptor antagonist that is under development for the treatment of… Expand
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Review
2019
Review
2019
Metastatic prostate cancer patients present in two ways—with already disseminated disease at the time of presentation or with… Expand
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Review
2018
Review
2018
Despite many recent advances in the therapy for metastatic castration-resistant prostate cancer (mCRPC), the disease remains… Expand
Review
2018
Review
2018
Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four… Expand
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Review
2018
Review
2018
Importance Targeted alpha therapy attempts to deliver systemic radiation selectively to cancer cells while minimizing systemic… Expand
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Review
2018
Review
2018
CONTEXT Although the widespread use of prostate-specific antigen (PSA) has led to an early detection of prostate cancer (PCa) and… Expand
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Review
2018
Review
2018
With increases in the mortality rate and number of patients with prostate cancer (PCa), PCa, particularly the advanced and… Expand
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Review
2018
Review
2018
Purpose: The purpose of this amendment is to incorporate newly‐published literature to provide a rational basis for the… Expand
Review
2017
Review
2017
The androgen-signaling axis plays a pivotal role in the pathogenesis of prostate cancer. Since the landmark discovery by Huggins… Expand
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