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Caricotamide

Known as: 1-(2-Amino-2-oxoethyl)-1,4-dihydropyridine-3-carboxamide 
A synthetic co-substrate that activates the human endogenous enzyme NRH:quinone oxidoreductase 2 (NQO2) with potential chemoadjuvant activity. When… 
National Institutes of Health

Papers overview

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2008
2008
Preliminary results of a Cancer Research UK phase I trial combining the dinitrobenzamide prodrug CB1954 (tretazicar) and the NQO2 substrate EP-0152R (caricotamide) intravenously (IV) every 3 weeks
2505 Background: CB1954 (CB) is a dinitrobenzamide prodrug that is converted in the presence of the enzyme NQO2 and co-substrate… 
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