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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1

Known as: Biliary Glycoprotein 1, CD66a Antigen, CEACAM1 
Carcinoembryonic antigen-related cell adhesion molecule 1 (526 aa, ~58 kDa) is encoded by the human CEACAM1 gene. This protein is involved in… 
National Institutes of Health

Related topics

Related topics

7 relations
CEACAM1 geneCarcinoembryonic AntigenGenes, RegulatorImmunoglobulin C2-set Domain

Broader (1)

Lymphocyte antigen CD66A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Pivotal Advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19‐mediated adhesion of B cells in a PI3K‐dependent manner
Upon antigen binding, the BCR transduces a signal culminating in proliferation or in AICD of the B cell. Coreceptor engagement… 
Highly Cited
2009
Highly Cited
2009
The CEACAM1 N-terminal Ig domain mediates cis- and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters
Structural analyses reveal that oligomerization between cell adhesion molecules in the same membrane is influenced by their… 
Highly Cited
2008
Highly Cited
2008
CEACAM1 Dynamics during Neisseria gonorrhoeae Suppression of CD4+ T Lymphocyte Activation1
Neisseria gonorrhoeae colony opacity-associated (Opa) proteins bind to human carcinoembryonic antigen cellular adhesion molecules… 
Highly Cited
2007
Highly Cited
2007
A Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Homologue Plays a Pivotal Role in Nontypeable Haemophilus influenzae Colonization of the Chinchilla Nasopharynx via the Outer Membrane…
ABSTRACT In vitro studies suggest an important role for CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) in… 
Highly Cited
2006
Highly Cited
2006
CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via Lewis x residues.
The CEA-related cell adhesion molecule 1, CEACAM1, is a glycoprotein expressed on the surface of human granulocytes and… 
Highly Cited
2003
Highly Cited
2003
CEACAM1-4S, a cell–cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture
In a 3D model of breast morphogenesis, CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) plays an essential… 
Highly Cited
2002
Highly Cited
2002
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family
CEACAM1 is a member of the carcinoembryonic antigen (CEA) family. Isoforms of murine CEACAM1 serve as receptors for mouse… 
Highly Cited
2001
Highly Cited
2001
The variable P5 proteins of typeable and non‐typeable Haemophilus influenzae target human CEACAM1
Haemophilus influenzae, a commensal of the human respiratory mucosa, is an important cause of localized and systemic infections… 
Highly Cited
2001
Highly Cited
2001
Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site.
CEACAM1 on leukocytic, endothelial, and epithelial cells functions in homophilic adhesion, tumor suppression, regulating cell… 
Highly Cited
2001
Highly Cited
2001
Targeted Disruption of the Ceacam1(MHVR) Gene Leads to Reduced Susceptibility of Mice to Mouse Hepatitis Virus Infection
ABSTRACT The CEACAM1 glycoproteins (formerly called biliary glycoproteins; BGP, C-CAM, CD66a, or MHVR) are members of the… 
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