Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Canfosfamide

Known as: (2R)-L-gamma-Glutamyl-3-((2-((bis(bis(2-chloroethyl)amino)phosphinyl)oxy)ethyl)sulfonyl)-L-alanyl-2-phenylglycine 
A modified glutathione analogue and nitrogen mustard prodrug, with potential antineoplastic activity. Canfosfamide is selectively activated by… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
LBA5528 Background: Canfosfamide (C) is a novel glutathione analog prodrug activated by glutathione S-transferase P1–1. P… Expand
Is this relevant?
2014
2014
TO THE EDITOR: Most phase III randomized clinical trials (RCT) in oncology are designed to change clinical practice by… Expand
Is this relevant?
2013
2013
Canfosfamide (TLK286, TELCYTA) is a prodrug that upon activation by glutathione transferase P1-1 (GST P1-1) yields an anticancer… Expand
Is this relevant?
Review
2012
Review
2012
The vulnerability of some cancer cells to oxidative signals is a therapeutic target for the rational design of new anticancer… Expand
  • table I
  • table II
  • figure 1
  • table III
Is this relevant?
2010
2010
BackgroundCanfosfamide is a novel glutathione analog activated by glutathione S-transferase P1-1. This study evaluated the safety… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
Review
2010
Review
2010
IntroductionOvarian cancer is a difficult to treat cancer entity with a high relapse rate. After initial surgery and chemotherapy… Expand
  • figure 1
  • figure 2
Is this relevant?
2009
2009
INTRODUCTION We aimed to evaluate the safety and efficacy of canfosfamide in combination with carboplatin and paclitaxel as first… Expand
Is this relevant?
Review
2009
Review
2009
5552 Background: Canfosfamide (C) is a glutathione analog prodrug activated by glutathione S-transferase P1-1. C is synergistic… Expand
Is this relevant?
Review
2007
Review
2007
LBA5529 Background: Canfosfamide (C) is a novel glutathione analog prodrug activated by glutathione S-transferase P1–1. C has… Expand
Is this relevant?