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Campath 1G

Known as: Campath-1-G, Campath-1G, Rat IgG2b Monoclonal Antibody CD52 
A rat IgG2b monoclonal antibody directed against the cell surface glycoprotein CD52. It is used in hematopoietic stem cell transplantation to prevent… 
National Institutes of Health

Related topics

Related topics

3 relations
CD52 protein, humanantigen binding

Broader (1)

alemtuzumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
T-cell depleting antibodies: new hope for induction of allograft tolerance in bone marrow transplantation?
Graft versus host disease (GVHD) remains the main barrier to successful allogeneic bone marrow transplant outcomes. Depletion of… 
2002
2002
CMV infection following nonmyeloablative allogeneic stem cell transplantation using Campath.
We would like to comment on the recent report by Chakrabarti et al[1][1] on the risk of cytomegalovirus (CMV) infection following… 
Highly Cited
2001
Highly Cited
2001
Improved outcome of alternative donor bone marrow transplantation in children with severe aplastic anaemia using a conditioning regimen containing low‐dose total body irradiation, cyclophosphamide…
The increasing success of human leucocyte antigen (HLA)‐matched sibling donor (MSD) transplants and combination immunosuppressive… 
1998
1998
Unrelated donor marrow transplantation for inborn errors.
From December 1989 to December 1997 40 children aged 1 year to 19 years with inborn errors other than severe combined… 
1998
1998
Haploidentical related transplants and unrelated donor transplants with T cell addback.
Only 30% of children have a matched family donor (MFD). Alternative donors can be found from volunteer unrelated donor (UD… 
1996
1996
Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA…
We have evaluated the effect of in vivo Campath-1G on engraftment and GVHD in 23 patients with severe aplastic anaemia… 
1996
1996
Transplantation of peripheral blood progenitor cells from unrelated donors.
Six patients with high risk haematological malignancies received peripheral blood progenitor cells (PBPC) from unrelated donors… 
1994
1994
T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease.
Campath-1G is an immunosuppressive monoclonal antibody directed against human lymphocytes. Its effectiveness in preventing graft… 
1993
1993
Graft rejection by a population of primed CDw52- host T cells after in vivo/ex vivo T-depleted bone marrow transplantation.
We investigated a case of graft rejection after in vivo/ex vivo T-depleted BMT in a patient who had received a HVG-matched, GVH… 
1990
1990
Comparative analysis of in vivo T cell depletion with radiotherapy, combination chemotherapy, and the monoclonal antibody Campath-1G, using limiting dilution methodology.
We have investigated the efficacy of standard conditioning regimens for bone marrow transplantation in depleting functional T… 
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