Calcimycin

Known as: Calcimycin [Chemical/Ingredient], 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-, 5-(Methylamino)-2-(((2R,3R,6S,8S,9R,11R)-3,9,11-Trimethyl-8-((1S)-1-Methyl-2-Oxo-2-(1H-Pyrrol-2-yl)Ethyl)-1,7-Dioxaspiro(5.5)Undec-2-yl)Methyl)-4-Benzoxazolecarboxylic Acid 
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes… (More)
National Institutes of Health

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Topic mentions per year

1984-2017
012319842017

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2013
2013
Calcimycin is a rare divalent cation specific ionophore antibiotic that has many biochemical and pharmaceutical applications. We… (More)
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2011
2011
The calcium-binding protein S100A4 is a central mediator of metastasis formation in colon cancer. S100A4 is a target gene of the… (More)
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Highly Cited
2005
Highly Cited
2005
The ocular lens is the only organ that does not develop spontaneous tumor. The molecular mechanism for this phenomenon remains… (More)
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2005
2005
The ocular lens is the only organ that does not develop spontaneous tumor. The molecular mechanism for this phenomenon remains… (More)
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2004
2004
OBJECT Although abnormalities in the control of endothelial vasomotility have been reported in both experimental and clinical… (More)
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2001
2001
As a model of the cell proliferation occurring in posterior capsule opacification (PCO), lens epithelial cells (LEC) from human… (More)
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1996
1996
1. The ability of calcimycin, cyclopiazonic acid and thapsigargin to facilitate the N-methyl-D-aspartate (NMDA)-mediated… (More)
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1995
1995
Previous studies have shown that calcimycin induces cataract in organ culture. To investigate the mechanism of this induction… (More)
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1991
1991
We examined the effect of elevating intracellular calcium ([Ca2+]i) on responses to iontophoretically applied N-methyl-D… (More)
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1990
1990
The effects of dauricine (Dau) on the release of platelet activating factor (PAF) from mouse peritoneal macrophages stimulated by… (More)
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