CYP2D6*41 Allele

Known as: Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*41 Allele, CYP2D6, g.2850C>T, g.4180G>C, CYP2D6, R296C, S486T 
Human CYP2D6*41 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
012320042017

Papers overview

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2016
2016
The pharmacokinetics of dextromethorphan (DM) is markedly influenced by cytochrome P450 2D6 (CYP2D6) enzyme polymorphisms. The… (More)
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2015
2015
OBJECTIVE The effects of various polymorphisms in cytochrome P450 (CYP) enzyme and transporter genes on the pharmacokinetics (PK… (More)
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2014
2014
Cytochrome P450 2D6 (CYP2D6) is involved in the metabolism of 25% of clinically used drugs. Genetic polymorphisms cause… (More)
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2014
2014
It has been suggested that the reduced function allele with reduced cytochrome P450 (CYP) 2D6 activity, CYP2D6*10, is associated… (More)
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2013
2013
The main objective of this study was to evaluate CYP2D6 genetic polymorphism in a Saudi Arabian population by determining the… (More)
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2011
2011
CYP2D6 belongs to the cytochrome P450 superfamily of enzymes and plays an important role in the metabolism of 20-25% of… (More)
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2010
2010
The pharmacokinetics of dextromethorphan (DM) is markedly influenced by cytochrome P450 2D6 (CYP2D6) enzyme polymorphisms. The… (More)
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2007
2007
We investigated the pharmacokinetics (PK) of aripiprazole, a newly developed antipsychotic, and its active metabolite in healthy… (More)
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2005
2005
The -1584C/G single nucleotide polymorphism (SNP) in the promoter region of CYP2D6 was suggested to have the potential to… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Individuals with the cytochrome P450 (CYP) 2D6 intermediate metabolizer (IM) phenotype have low residual enzyme… (More)
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