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CYM-5442

 
National Institutes of Health

Papers overview

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2019
2019
Neuropathic pain correlates with a lesion or other dysfunction in the nervous system. Sphingosine-1-phosphate receptor 2 (S1P2… Expand
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2018
2018
High-density lipoprotein (HDL) has previously been shown to promote angiogenesis. However, the mechanisms by which HDL enhances… Expand
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2018
2018
The immunomodulatory prodrug 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol (FTY720), which acts as an agonist for… Expand
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2017
2017
ABSTRACT We investigated the feasibility and efficacy of using a specific sphingosine 1–phosphate (S1P1) receptor agonist, CYM… Expand
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2017
2017
Blockade of IFN-α but not IFN-β signaling using either an antibody or a selective S1PR1 agonist, CYM-5442, prevented type 1… Expand
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2015
2015
FTY720, an agonist for four of the five known sphingosine-1-phosphate (S1P) receptors, has been reported to inhibit acute graft… Expand
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2015
2015
BackgroundSphingosine-1-phosphate (S1P) is a bioactive sphingolipid that acts through a family of five G-protein-coupled… Expand
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2014
2014
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a critical dose-limiting side effect of many chemotherapeutic… Expand
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2012
2012
Multiple sclerosis (MS) therapies modulate T-cell autoimmunity in the central nervous system (CNS) but may exacerbate latent… Expand
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Highly Cited
2008
Highly Cited
2008
Strong evidence exists for interactions of zwitterionic phosphate and amine groups in sphingosine-1 phosphate (S1P) to conserved… Expand
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