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CYM-5442

National Institutes of Health

Papers overview

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2019
2019
The pandemic 2009 influenza A H1N1 virus is associated with significant mortality. Targeting S1PR1, which is known to modulate… 
2018
2018
High-density lipoprotein (HDL) has previously been shown to promote angiogenesis. However, the mechanisms by which HDL enhances… 
2018
2018
The immunomodulatory prodrug 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol (FTY720), which acts as an agonist for… 
2017
2017
Significance Type 1 diabetes (T1D) is an increasing medical health problem caused by autoimmune T cells killing insulin-producing… 
2015
2015
FTY720, an agonist for four of the five known sphingosine-1-phosphate (S1P) receptors, has been reported to inhibit acute graft… 
2015
2015
BackgroundSphingosine-1-phosphate (S1P) is a bioactive sphingolipid that acts through a family of five G-protein-coupled… 
Highly Cited
2014
Highly Cited
2014
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a critical dose-limiting side effect of many chemotherapeutic… 
Highly Cited
2012
Highly Cited
2012
Multiple sclerosis (MS) therapies modulate T-cell autoimmunity in the central nervous system (CNS) but may exacerbate latent… 
Highly Cited
2008
Highly Cited
2008
Strong evidence exists for interactions of zwitterionic phosphate and amine groups in sphingosine-1 phosphate (S1P) to conserved…