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CYBA gene

Known as: CYBA, flavocytochrome b-558 alpha polypeptide, cytochrome b-245 alpha chain 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Resveratrol decreases fructose‐induced oxidative stress, mediated by NADPH oxidase via an AMPK‐dependent mechanism
Oxidative stress is an important pathogenic factor in the development of hypertension. Resveratrol, the main antioxidant in red… 
Review
2008
Review
2008
NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases.
Oxidative stress plays a key role in the pathophysiology of several major cardiovascular diseases, including atherosclerosis… 
Highly Cited
2006
Highly Cited
2006
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension
Objective Oxidative stress is implicated in hypertension. The reduced nicotinamide adenine dinucleotide phosphate (NADPH… 
Highly Cited
2001
Highly Cited
2001
Differential NADPH- versus NADH-dependent superoxide production by phagocyte-type endothelial cell NADPH oxidase.
Review
1996
Review
1996
Interactions between the components of the human NADPH oxidase: intrigues in the phox family.
Highly Cited
1995
Highly Cited
1995
Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries.
During assembly of the phagocyte NADPH oxidase, cytosolic p47-phox translocates to the plasma membrane and binds to… 
Highly Cited
1994
Highly Cited
1994
Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.
The NADPH oxidase responsible for generation of superoxide anion and related microbicidal oxidants by phagocytes is assembled… 
Highly Cited
1994
Highly Cited
1994
156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
Src homology 3 (SH3) domains have been suggested to play an important role in the assembly of the superoxide-forming nicotinamide… 
Highly Cited
1991
Highly Cited
1991
Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease.
The NADPH:O2 oxidoreductase of phagocytic leukocytes is an important enzyme for the bactericidal activity of these cells… 
Highly Cited
1979
Highly Cited
1979
The multiplicity and stoichiometry of the prosthetic groups in QH2: cytochrome c oxidoreductase as studied by EPR.
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