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CV 2619

Known as: CV-2619 
National Institutes of Health

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Broader (1)

idebenone

Papers overview

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Review
1990
Review
1990
Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review.
1986
1986
[Brain distribution of idebenone (CV-2619) and its effect on local cerebral glucose utilization in rats].
To investigate the possible action-sites of a cerebral metabolism activator, idebenone (CV-2619), its distribution in the brain… 
1985
1985
Disposition of idebenone (CV-2619), a new cerebral metabolism improving agent, in rats and dogs.
After oral administration of 14C-labeled idebenone (14C-CV-2619) to rats, the plasma 14C level reached a plateau at 15 min, which… 
Highly Cited
1985
Highly Cited
1985
Effect of idebenone (CV-2619) on memory impairment observed in passive avoidance task in rats with cerebral embolization.
Effect of idebenone (CV-2619) on memory impairment was studied in rats with cerebral embolization. The cerebral embolization… 
1985
1985
Effects of idebenone (CV-2619) on metabolism of monoamines, especially serotonin, in the brain of normal rats and rats with cerebral ischemia.
The effects of 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619) on the contents, turnover… 
1985
1985
Metabolism of idebenone (CV-2619), a new cerebral metabolism improving agent: isolation and identification of metabolites in the rat and dog.
Metabolic studies of idebenone (CV-2619), a new cerebral metabolism improving agent, in the rat and dog by thin-layer… 
1985
1985
[Effect of idebenone (CV-2619) on brightness discrimination learning in rats with central serotonergic dysfunction].
The effect of 6-(10-hydroxydecyl)-2, 3-dimethoxy-5-methyl-1, 4-benzoquinone (idebenone, CV-2619) on brightness discrimination… 
Highly Cited
1984
Highly Cited
1984
Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats.
An experimental model of amnesia induced by cerebral ischemia after one-trial passive avoidance learning was established to test… 
Highly Cited
1984
Highly Cited
1984
Effects of idebenone (CV-2619) on the concentrations of acetylcholine and choline in various brain regions of rats with cerebral ischemia.
The concentrations of acetylcholine (Ach) and choline in various brain regions of rats with and without cerebral ischemia and the… 
1984
1984
[Effects of idebenone (CV-2619) on neurological deficits, local cerebral blood flow, and energy metabolism in rats with experimental cerebral ischemia].
Improvement of energy metabolism in ischemic cerebral tissue benefits the therapy of occlusive cerebrovascular lesions. In the… 
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