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CV 2619

Known as: CV-2619 
National Institutes of Health

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Broader (1)

idebenone

Papers overview

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Review
1990
Review
1990
Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review.
Highly Cited
1985
Highly Cited
1985
Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs.
The effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in isolated brain… 
1985
1985
Disposition of idebenone (CV-2619), a new cerebral metabolism improving agent, in rats and dogs.
After oral administration of 14C-labeled idebenone (14C-CV-2619) to rats, the plasma 14C level reached a plateau at 15 min, which… 
Highly Cited
1985
Highly Cited
1985
Effect of idebenone (CV-2619) on memory impairment observed in passive avoidance task in rats with cerebral embolization.
Effect of idebenone (CV-2619) on memory impairment was studied in rats with cerebral embolization. The cerebral embolization… 
Highly Cited
1984
Highly Cited
1984
Inhibition of lipid peroxidation by a novel compound, idebenone (CV-2619).
(A. Nagaoka et al., unpublished data). In the present study, we examined the effects of CV-2619 on lipid peroxidation in brain… 
Highly Cited
1984
Highly Cited
1984
Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats.
An experimental model of amnesia induced by cerebral ischemia after one-trial passive avoidance learning was established to test… 
Highly Cited
1984
Highly Cited
1984
Effects of idebenone (CV-2619) on the concentrations of acetylcholine and choline in various brain regions of rats with cerebral ischemia.
The concentrations of acetylcholine (Ach) and choline in various brain regions of rats with and without cerebral ischemia and the… 
1984
1984
Inhibitory effect of idebenone (CV-2619), a novel compound, on vascular lesions in hypertensive rats.
The effects of a novel compound, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619), on cerebral… 
Highly Cited
1984
Highly Cited
1984
Inhibition of lipid peroxidation by a novel compound (CV-2619) in brain mitochondria and mode of action of the inhibition.
1984
1984
[Effects of idebenone (CV-2619) on neurological deficits, local cerebral blood flow, and energy metabolism in rats with experimental cerebral ischemia].
Improvement of energy metabolism in ischemic cerebral tissue benefits the therapy of occlusive cerebrovascular lesions. In the… 
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