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CV 2619

Known as: CV-2619 
 
National Institutes of Health

Papers overview

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2000
2000
In this study, we examined the effect of the neuroprotective agent 2, 3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone… Expand
Highly Cited
1985
Highly Cited
1985
The effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in isolated brain… Expand
Highly Cited
1985
Highly Cited
1985
The effects of 6‐(10‐hydroxydecyl)‐2,3‐dimethoxy‐5‐methyl‐l,4‐benzoquinone (CV‐2619) on the respiration and non‐respiratory… Expand
1985
1985
After oral administration of 14C-labeled idebenone (14C-CV-2619) to rats, the plasma 14C level reached a plateau at 15 min, which… Expand
Highly Cited
1985
Highly Cited
1985
Effect of idebenone (CV-2619) on memory impairment was studied in rats with cerebral embolization. The cerebral embolization… Expand
Highly Cited
1984
Highly Cited
1984
An experimental model of amnesia induced by cerebral ischemia after one-trial passive avoidance learning was established to test… Expand
Highly Cited
1984
Highly Cited
1984
Lipid peroxidation in rat brain mitochondria was induced by NADH in the presence of ADP and FeCl3. CV-2619 inhibited the lipid… Expand
Highly Cited
1984
Highly Cited
1984
(A. Nagaoka et al., unpublished data). In the present study, we examined the effects of CV-2619 on lipid peroxidation in brain… Expand
Highly Cited
1984
Highly Cited
1984
The concentrations of acetylcholine (Ach) and choline in various brain regions of rats with and without cerebral ischemia and the… Expand
1984
1984
The effects of a novel compound, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619), on cerebral… Expand