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CTS-21166

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Potential novel targets for Alzheimer pharmacotherapy: II. Update on secretase inhibitors and related approaches
The prevailing theory regarding Alzheimer disease (AD) is that insoluble amyloid β‐peptide (Aβ) plays a critical role in the… 
Review
2009
Review
2009
Disease-Modifying Approach to the Treatment of Alzheimer’s Disease
In the last decade, advances in understanding the neurobiology of Alzheimer’s disease (AD) have translated into an increase in… 
  • figure 1
  • table I
  • figure 2
  • figure 3
Review
2009
Review
2009
Beyond the neurotransmitter-focused approach in treating Alzheimer’s Disease: drugs targeting β-amyloid and tau protein
Drugs currently used to treat Alzheimer’s Disease (AD) have limited therapeutic value and do not affect the main… 
Review
2009
Review
2009
Progress in the development of beta-secretase inhibitors for Alzheimer's disease.
  • J. Albert
  • Progress in medicinal chemistry
  • 2009
  • Corpus ID: 42170813
Since the original identification of BACE in 1999 and until quite recently, BACE was often regarded as a "difficult" drug target… 
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