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BACKGROUND AND OBJECTIVES
The progression of kidney disease in some patients with type 2 diabetes mellitus may not be adequately… Expand Mineralocorticoid receptors (MRs) are implicated in the pathology of hypertension. MR blockers are recommended for the treatment… Expand Although beneficial antihypertensive and antialbuminuric effects of steroidal mineralocorticoid receptor (MR) antagonists have… Expand This was a phase 2, multicenter, randomized, double-blind, placebo-controlled, open-label comparator study to investigate the… Expand Esaxerenone (CS-3150) is a novel, nonsteroidal, selective mineralocorticoid receptor blocker. The absorption, metabolism… Expand Herein, we studied the effects of the novel nonsteroidal selective mineralocorticoid receptor (MR) blocker, esaxerenone, on blood… Expand Objective: ESAX-HTN study is a randomized, double-blind phase III study of esaxerenone (CS-3150), a novel non-steroidal… Expand The present study was designed to assess both preventive and therapeutic effects of (S)-1-(2-Hydroxyethyl)-4-methyl-N-[4… Expand The present study was designed to characterize the pharmacological profile of CS-3150, a novel non-steroidal mineralocorticoid… Expand The present study was designed to evaluate the antihypertensive and cardiorenal protective effects of CS-3150, a novel non… Expand