CRISPR-Associated Protein Complex Proteins

Known as: CASCADE Proteins, CRISPR Associated, CASCADE Proteins, CRISPR-Associated, CRISPR-Associated Complex for Antiviral Defense Proteins 
Proteins in RIBONUCLEOPROTEIN assemblies of CRISPR-CAS SYSTEMS that function in targeting DNA of invading viruses and plasmids.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
05020072017

Papers overview

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Highly Cited
2015
Highly Cited
2015
The utility of CRISPR-Cas9 and TALENs for genome editing may be compromised by their off-target activity. We show that integrase… (More)
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Highly Cited
2015
Highly Cited
2015
Although RNA-guided genome editing via the CRISPR-Cas9 system is now widely used in biomedical research, genome-wide target… (More)
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Highly Cited
2015
Highly Cited
2015
CRISPR-Cas9 technology provides a powerful system for genome engineering. However, variable activity across different single… (More)
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Highly Cited
2015
Highly Cited
2015
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA… (More)
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Highly Cited
2011
Highly Cited
2011
Precise RNA processing is fundamental to all small RNA-mediated interference pathways. In prokaryotes, clustered, regularly… (More)
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Highly Cited
2009
Highly Cited
2009
Compelling evidence indicates that the CRISPR-Cas system protects prokaryotes from viruses and other potential genome invaders… (More)
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Highly Cited
2009
Highly Cited
2009
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated CRISPR-associated sequence (CAS) proteins… (More)
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Highly Cited
2008
Highly Cited
2008
Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the… (More)
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Highly Cited
2008
Highly Cited
2008
Clustered regularly interspaced short palindromic repeats (CRISPR) are hypervariable loci widely distributed in prokaryotes that… (More)
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