CRBN, ARG419TER
National Institutes of Health
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Immunomodulatory compounds, IMiDs® lenalidomide and pomalidomide mediate their anti-myeloma activities via cereblon, a component…
Cereblon (CRBN) as a multifunctional protein has been extensively studied. Here, we show that CRBN is a negative regulator of…
Mutations in the cereblon (CRBN) gene cause human intellectual disability, one of the most common cognitive disorders. However…
Cereblon (CRBN) is a substrate receptor of the E3 ubiquitin ligase complex that has been linked to autosomal recessive non…