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CPU228

National Institutes of Health

Papers overview

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2010
2010
CPU228, a derivative of dofetilide, relieves cardiac dysfunction by normalizing FKBP12.6, NADPH oxidase and protein kinase C ε in the myocardium
Objectives The aim of this study was to determine if CPU228, a derivative of dofetilide, is more effective than dofetilide in… 
2007
2007
CALCIUM ANTAGONIST PROPERTY OF CPU228, A DOFETILIDE DERIVATIVE, CONTRIBUTES TO ITS LOW INCIDENCE OF TORSADES DE POINTES IN RABBITS
1 Torsades de pointes (TDP) is a severe adverse effect during the clinical use of dofetilide, a selective blocker of the rapid… 
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