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CP 263114

Known as: CP 263,114, CP-263,114, CP-263114 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Maleic Anhydridesphomoidride B

Papers overview

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Highly Cited
2002
Highly Cited
2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy.
Crucial model synthetic and mechanistic studies directed toward the development of methodology for the construction of the maleic… Expand
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2002
2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo[4.3.1] key building blocks.
A brief introduction into the chemistry of the CP-molecules is followed by first-generation synthetic sequences toward key… Expand
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2001
2001
Evolution of a synthetic approach to CP-263,114.
[structure: see text] Three different approaches to the carbocyclic core of CP-263,114 are presented that illustrate a strategic… Expand
2001
2001
Application of Lewis acid catalyzed tropone [6+4] cycloadditions to the synthesis of the core of CP-225,917.
The carbocyclic core of CP-225,917 and CP-263,114 is accessible through the [6+4] cycloaddition of a tropone with a 2-substituted… Expand
2000
2000
Investigations into a biomimetic approach toward CP-225,917 and CP-263,114.
A biosynthesis of the structurally complex nonadride CP-225,917 (1) is outlined. A key step in this proposal is the dimerization… Expand
2000
2000
An exploratory study of type II [3 + 4] cycloadditions between vinylcarbenoids and dienes.
The intramolecular type II [3 + 4] cycloaddition between vinylcarbenoids and furans is a practical method for the construction of… Expand
Highly Cited
1999
Highly Cited
1999
Total Synthesis of the CP Molecules CP-225,917 and CP-263,114- Part 2: Evolution of the Final Strategy.
 
Highly Cited
1999
Highly Cited
1999
Total Synthesis of the CP Molecules CP-263,114 and CP-225,917- Part 1: Synthesis of Key Intermediates and Intelligence Gathering.
A synthetic labyrinth endowed with countless obstacles, yet filled with numerous hidden treasures, had to be overcome to reach… Expand
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1998
1998
Stereospecific Synthesis of the CP-263,114 Core Structure
CP-263,114 (1) is a fungal metabolite that was isolated1,2 as part of a program to identify inhibitors of Ras… Expand
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Highly Cited
1997
Highly Cited
1997
CP-225,917 and CP-263,114, novel Ras farnesylation inhibitors from an unidentified fungus. I. Taxonomy, fermentation, isolation, and biochemical properties.
During the course of our screening for squalene synthase inhibitors and Ras farnesylation inhibitors, a novel fungal culture was… Expand
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