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CP 263114

Known as: CP 263,114, CP-263,114, CP-263114 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Maleic Anhydridesphomoidride B

Papers overview

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2002
2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo[4.3.1] key building blocks.
A brief introduction into the chemistry of the CP-molecules is followed by first-generation synthetic sequences toward key… 
2002
2002
Studies on the biosynthesis of phomoidride B (CP-263,114): evidence for a decarboxylative homodimerization pathway.
[reaction: see text]. Feeding experiments using a deuterium labeled C16 maleic anhydride and whole cell culture of ATCC 74256 led… 
2001
2001
Investigations into the production and interconversion of phomoidrides A-D.
[structure: see text] Fermentation of ATCC 74256 led to the isolation and identification of C7 epimers of phomoidride A (CP-225… 
2000
2000
Syntheses of CP-225,917 and CP-263,114.
Highly Cited
1999
Highly Cited
1999
Total Synthesis of the CP Molecules CP-263,114 and CP-225,917- Part 1: Synthesis of Key Intermediates and Intelligence Gathering.
A synthetic labyrinth endowed with countless obstacles, yet filled with numerous hidden treasures, had to be overcome to reach… 
Highly Cited
1999
Highly Cited
1999
Total Synthesis of the CP Molecules CP-225,917 and CP-263,114- Part 2: Evolution of the Final Strategy.
1999
1999
Discovery Through Total Synthesis-Epimerization at C7 in the CP Compounds: Is (7S)-CP-263,114 a Fermentation Product?
Sometimes a surprise can occur in a total synthesis. The preparative investigation of the title compound CP-263,114 and of CP-225… 
1998
1998
Stereospecific Synthesis of the CP-263,114 Core Structure
CP-263,114 (1) is a fungal metabolite that was isolated1,2 as part of a program to identify inhibitors of Ras… 
1998
1998
Synthetic studies of nonadrides
approved: James D. White An asymmetric approach to the synthesis of byssochlamic acid (1) is described. Regioisomeric enzymatic… 
Highly Cited
1997
Highly Cited
1997
CP-225,917 and CP-263,114, novel Ras farnesylation inhibitors from an unidentified fungus. I. Taxonomy, fermentation, isolation, and biochemical properties.
During the course of our screening for squalene synthase inhibitors and Ras farnesylation inhibitors, a novel fungal culture was… 
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