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CP 225917

Known as: CP 225,917, CP-225,917, CP-225917 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Maleic Anhydridesphomoidride A

Papers overview

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2009
2009
Formation of carbocycles by intramolecular conjugate displacement: scope and mechanistic insights.
A detailed study has been made of a method of ring closure categorized as an all-carbon intramolecular conjugate displacement… 
2002
2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo[4.3.1] key building blocks.
A brief introduction into the chemistry of the CP-molecules is followed by first-generation synthetic sequences toward key… 
2001
2001
Investigations into the production and interconversion of phomoidrides A-D.
[structure: see text] Fermentation of ATCC 74256 led to the isolation and identification of C7 epimers of phomoidride A (CP-225… 
2000
2000
Syntheses of CP-225,917 and CP-263,114.
Highly Cited
1999
Highly Cited
1999
Total Synthesis of the CP Molecules CP-225,917 and CP-263,114- Part 2: Evolution of the Final Strategy.
1999
1999
Discovery Through Total Synthesis-Epimerization at C7 in the CP Compounds: Is (7S)-CP-263,114 a Fermentation Product?
Sometimes a surprise can occur in a total synthesis. The preparative investigation of the title compound CP-263,114 and of CP-225… 
1999
1999
Novel strategies to construct the gamma-hydroxy lactone moiety of the CP molecules. Synthesis of the CP-225,917 core skeleton.
[formula: see text] The array of challenging structural lineaments embodied in the CP molecules (1 and 2, Figure 1) offers… 
1998
1998
Synthetic studies of nonadrides
approved: James D. White An asymmetric approach to the synthesis of byssochlamic acid (1) is described. Regioisomeric enzymatic… 
Highly Cited
1997
Highly Cited
1997
CP-225,917 and CP-263,114, novel Ras farnesylation inhibitors from an unidentified fungus. I. Taxonomy, fermentation, isolation, and biochemical properties.
During the course of our screening for squalene synthase inhibitors and Ras farnesylation inhibitors, a novel fungal culture was… 
1997
1997
Efforts toward the total syntheses of phorbol and CP-225917
The total synthesis of complex natural products is a challenging and sometimes rewarding assignment. Progress in the routes to… 
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