Skip to search formSkip to main contentSkip to account menu

COL4A3 gene

Known as: Collagen, Type IV, Alpha 3 (Goodpasture Antigen) Gene, collagen type IV alpha 3, COL4A3 
This gene plays a role in the compositional and structural regulation of basement membranes.
National Institutes of Health

Related topics

Related topics

12 relations
Alport SyndromeAnti-Glomerular Basement Membrane DiseaseCOL4A3BP geneCell Adhesion

Narrower (1)

COL4A3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The interface of genetics with pathology in alport nephritis.
Alport syndrome (AS) is a rare disorder characterized by deafness, ocular abnormalities, and progressive renal failure. One of… 
2013
2013
Tumstatin transfected into human glioma cell line U251 represses tumor growth by inhibiting angiogenesis
Background Angiogenesis is a prerequisite for tumor growth and plays an important role in rapidly growing tumors, such as… 
2012
2012
Decreased tumstatin‐mRNA is associated with poor outcome in patients with NSCLC
Tumstatin is a candidate tumor suppressor that plays an important role in tumor growth and angiogenesis. The purpose of this… 
2010
2010
Novel heterozygous COL4A3 mutation in a family with late-onset ESRD
Thin basement membrane nephropathy (TBMN) and Alport syndrome (ATS) are genetically heterogeneous conditions characterized by… 
2008
2008
Effects of cloned tumstatin-related and angiogenesis-inhibitory peptides on proliferation and apoptosis of endothelial cells.
BACKGROUND Tumstatin is a recently developed endogenous vascular endothelial growth inhibitor that can be applied as an anti… 
Highly Cited
2006
Highly Cited
2006
The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.
The collagen type IV cleavage fragment tumstatin and its active subfragments bind to integrin alpha(V)beta(3) and inhibit… 
2006
2006
Expression, purification, and bioactivity of human tumstatin from Escherichia coli.
2004
2004
Improved production of recombinant tumstatin in stably transformed Trichoplusia ni BTI Tn 5B1-4 cells.
2003
2003
Functional expression of recombinant tumstatin in stably transformed Drosophila melanogaster S2 cells
Recombinant tumstatin was expressed in stably transformed Drosophila melanogaster S2 cells and secreted into the medium with a… 
1993
1993
Discordant phenotype of two overlapping deletions involving the PAX3 gene in chromosome 2q35.
Waardenburg syndrome (WS), the most common form of inherited congenital deafness, is a pleiotropic, autosomal dominant condition… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)