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COL4A3 gene

Known as: Collagen, Type IV, Alpha 3 (Goodpasture Antigen) Gene, collagen type IV alpha 3, COL4A3 
This gene plays a role in the compositional and structural regulation of basement membranes.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes including inherited genetic defects with… Expand
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Highly Cited
2009
Highly Cited
2009
Purpose Alterations in collagen type IV, alpha-3 (COL4A3) and collagen type IV, alpha-4 (COL4A4) genes may be responsible for a… Expand
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Highly Cited
2004
Highly Cited
2004
In the early stage of diabetic nephropathy (one of the major microvascular complications of diabetes) glomerular hyperfiltration… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Alport syndrome is a clinically and genetically heterogeneous nephropathy. The majority of cases are transmitted as an… Expand
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Highly Cited
2003
Highly Cited
2003
We demonstrate a physiological role for tumstatin, a cleavage fragment of the α3 chain of type IV collagen (Col IVα3), which is… Expand
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Highly Cited
2003
Highly Cited
2003
We demonstrate a physiological role for tumstatin, a cleavage fragment of the alpha3 chain of type IV collagen (Col IValpha3… Expand
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Highly Cited
2003
Highly Cited
2003
Vascular endothelial growth factor (VEGF), a major factor mediating endothelial cell survival, migration, and proliferation… Expand
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Highly Cited
2002
Highly Cited
2002
Tumstatin is a 28-kilodalton fragment of type IV collagen that displays both anti-angiogenic and proapoptotic activity. Here we… Expand
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Highly Cited
2001
Highly Cited
2001
Components of vascular basement membrane are involved in regulating angiogenesis. Recently, tumstatin (the NC1 domain of α3 chain… Expand
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Highly Cited
2000
Highly Cited
2000
Vascular basement membrane is an important regulator of angiogenesis and undergoes many alterations during angiogenesis and these… Expand
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