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COA3 gene

Known as: HSPC009, CCDC56, COA3 
 
National Institutes of Health

Papers overview

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2017
2017
A CMC1-knockout reveals translation-independent control of human mitochondrial complex IV biogenesis.
Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly… Expand
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2017
2017
Gene Regulation Network Based Analysis Associated with TGF-βeta Stimulation in Lung Adenocarcinoma Cells
BACKGROUND Transforming growth factor (TGF)-β is over-expressed in a wide variety of cancers such as lung adenocarcinoma. TGF… Expand
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2016
2016
A Novel Function of Pet54 in Regulation of Cox1 Synthesis in Saccharomyces cerevisiae Mitochondria*
Cytochrome c oxidase assembly requires the synthesis of the mitochondria-encoded core subunits, Cox1, Cox2, and Cox3. In yeast… Expand
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2016
2016
Human COA3 Is an Oligomeric Highly Flexible Protein in Solution.
The assembly of the protein complex of cytochrome c oxidase (COX), which participates in the mitochondrial respiratory chain… Expand
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2015
2015
Mutations in COA3 cause isolated complex IV deficiency associated with neuropathy, exercise intolerance, obesity, and short stature.
BACKGROUND We investigated a subject with an isolated cytochrome c oxidase (COX) deficiency presenting with an unusual phenotype… Expand
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2015
2015
COX assembly factor ccdc56 regulates mitochondrial morphology by affecting mitochondrial recruitment of Drp1.
Mitochondria are dynamic organelles that alter their morphology in response to cellular signaling and differentiation through… Expand
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2013
2013
hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria.
Cytochrome c oxidase (COX) or complex IV of the mitochondrial respiratory chain plays a fundamental role in energy production of… Expand
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2013
2013
hCOA 3 stabilizes COX 1 and promotes cytochrome c oxidase assembly in human mitochondria
Cytochrome c oxidase (COX) or complex IV of the mitochondrial respiratory chain plays a fundamental role in energy production of… Expand
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2012
2012
Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function.
In Drosophila melanogaster, the mitochondrial transcription factor B1 (d-mtTFB1) transcript contains in its 5'-untranslated… Expand
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Highly Cited
2010
Highly Cited
2010
Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria
Regulation of eukaryotic cytochrome oxidase assembly occurs at the level of Cox1 translation, its central mitochondria-encoded… Expand
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