CNS metastases

Known as: Metastatic Neoplasm to the CNS, Metastatic Malignant Neoplasm to the Central Nervous System, metastases, CNS 
A malignant neoplasm that has spread to the central nervous system from another anatomic site or system. The majority are carcinomas (usually lung or… (More)

Topic mentions per year

Topic mentions per year

1975-2017
0204019752017

Papers overview

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Review
2014
Review
2014
INTRODUCTION Human epidermal growth factor receptor (HER) 2 is overexpressed in 20 - 25% of breast cancers, and has historically… (More)
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Highly Cited
2011
Highly Cited
2011
Erlotinib is effective for epidermal growth factor receptor (EGFR) mutant lung cancer, but CNS penetration at standard daily… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE registHER is a prospective, observational study of 1,023 newly diagnosed HER2-positive metastatic breast cancer (MBC… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Brain metastases develop in one third of patients with advanced HER2+ breast cancer. Effective therapy for patients with… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The purpose of the current study was to characterize the outcomes of patients with metastatic triple-negative breast… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The purpose of this retrospective study was to determine, in a cohort of patients with breast cancer and central… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We sought to determine whether a high-risk group could be defined among patients with operable breast cancer in whom a… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND There is anecdotal evidence that the incidence of central nervous system (CNS) metastases in breast cancer patients is… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The aim of this study was to characterize the prevalence and predictors of central nervous system (CNS) metastasis among… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Women with HER-2 overexpressing metastatic breast carcinoma benefit from trastuzumab-based therapy, but trastuzumab… (More)
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