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CN 100

Known as: CN-100 
National Institutes of Health

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1 relation

Broader (1)

Benzothiepins

Papers overview

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1991
1991
Pharmacokinetic Profile of a New Nonsteroidal Anti-Inflammatory Agent, CN-100, in Humans
SummaryA new, tricyclic, nonsteroidal anti-inflammatory agent, 2-(10,11-dihydro-10-oxodibenzo[b,f] thiepin-2-yl) propionic acid… 
1991
1991
[Effects of CN-100 on the functions of rat polymorphonuclear leukocytes].
We studied the effects of CN-100 on the functions of rat polymorphonuclear leukocytes (PMN) in vitro. CN-100 showed the… 
1990
1990
Optical resolution and absolute configuration of a nonsteroidal antiinflammatory drug, 2-(10,11-dihydro-10-oxodibenzo- [b,f]thiepin-2-yl)propionic acid.
The title compound (+/-)-1 (CN-100) was efficiently resolved into a pair of enantiomers by fractional crystallization of the… 
1990
1990
[Interaction of CN-100, a novel non-steroidal anti-inflammatory drug, on biopolymers].
Interaction of CN-100, a novel non-steroidal anti-inflammatory drug, with biopolymers were investigated. In collagen induced rat… 
1989
1989
[Effects of CN-100 (2-(10,11-dihydro-10-oxodibenzo [b,f] thiepin-2-yl) propionic acid) on cardiovascular and autonomic nervous function in the dog and guinea pig].
1) In pentobarbital-anesthetized dogs, intravenous administration of CN-100 at 40 mg/kg exhibited a transient hypotension… 
1987
1987
Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse.
Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid (CN-100) have been… 
1986
1986
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 1st communication: inhibitory effects of rat paw edema.
In the development process of a new nonsteroidal antiinflammatory drug (NSAID) with less toxicity and side-effects, 2-(10,11… 
1986
1986
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl]propionic acid. 4th communication: inhibitory effects on rat adjuvant arthritis.
The preventive and therapeutic effects of 2-(10,11-dihydro-10-oxodibenzo [b,f]thiepin-2-yl)propionic acid (CN-100) on local and… 
1986
1986
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 3rd communication: inhibitory effects on leucocyte emigration and…
The effects of 2-(10,11-dihydro-10-oxodibenzo [b,f]thiepin-2-yl)propionic acid (CN-100), which has a significant inhibitory… 
1986
1986
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 5th communication: antiplatelet effect of the drug and…
Since nonsteroidal antiinflammatory drugs (NSAID) usually have an antiplatelet effect, the inhibitory effect of 2-(10,11-dihydro… 
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