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CMX 157

Known as: CMX-157, CMX157 
National Institutes of Health

Papers overview

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2019
2019
Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema
2018
2018
Validation and implementation of liquid chromatographic‐mass spectrometric (LC–MS) methods for the quantification of tenofovir prodrugs
Review
2013
Review
2013
The antiretroviral drug pipeline: prospects and implications for future treatment research
Purpose of reviewA number of investigational antiretroviral drugs in clinical development could alter the future treatment… 
2010
2010
Development of Hexadecyloxypropyl Tenofovir (CMX157) for Treatment of Infection Caused by Wild-Type and Nucleoside/Nucleotide-Resistant HIV
ABSTRACT CMX157 is a lipid (1-0-hexadecyloxypropyl) conjugate of the acyclic nucleotide analog tenofovir (TFV) with activity… 
2010
2010
Nucleoside / Nucleotide-Resistant HIV Infection Caused by Wild-Type and Tenofovir ( CMX 157 ) for Treatment of Development of Hexadecyloxypropyl
Published Ahead of Print 3 May 2010. 10.1128/AAC.00068-10. 2010, 54(7):2901. DOI: Antimicrob. Agents Chemother. and George R… 
Highly Cited
2009
Highly Cited
2009
Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.
Highly Cited
2007
Highly Cited
2007
Evaluation of Hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)Propyl]-Adenine, CMX157, as a Potential Treatment for Human Immunodeficiency Virus Type 1 and Hepatitis B Virus Infections
9-R-[2-(Phosphonomethoxy)propyl]-adenine (tenofovir) is an acyclic nucleoside phosphonate with antiviral activity against human… 
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