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CLTCL1 wt Allele

Known as: Clathrin, Heavy Polypeptide D Gene, CHC17, FLJ36032 
Human CLTCL1 wild-type allele is located in the vicinity of 22q11.2 and is approximately 112 kb in length. This allele, which encodes clathrin heavy… Expand
National Institutes of Health

Related topics

Related topics

4 relations
CLTC geneCLTC wt AlleleReceptor Mediated Endocytosis

Broader (1)

CLTCL1 gene

Papers overview

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2012
2012
Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
Clathrin depletion by ribonucleic acid interference (RNAi) impairs mitotic spindle stability and cytokinesis. Depletion of… Expand
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2010
2010
The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step
Clathrin heavy chain 22 (CHC22) is an isoform of the well-characterized CHC17 clathrin heavy chain, a coat component of vesicles… Expand
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Highly Cited
2009
Highly Cited
2009
A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism.
Intracellular trafficking of the glucose transporter GLUT4 from storage compartments to the plasma membrane is triggered in… Expand
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2009
2009
Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.
Clathrin is crucial for endocytosis and plays a recently described role in mitosis. Two clathrin heavy chains (CHCs) are found in… Expand
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2005
2005
Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution.
In humans, there are two isoforms each of clathrin heavy chain (CHC17 and CHC22) and light chain (LCa and LCb) subunits, all… Expand
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2004
2004
Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.
The muscle isoform of clathrin heavy chain, CHC22, has 85% sequence identity to the ubiquitously expressed CHC17, yet its… Expand
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2001
2001
FM1-43 imaging reveals cGMP-dependent long-term depression of presynaptic transmitter release.
A persistent question concerning mechanisms underlying long-term, activity-dependent synaptic plasticity is whether the sites of… Expand
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2001
2001
A novel clathrin homolog that co-distributes with cytoskeletal components functions in the trans-Golgi network.
A clathrin homolog encoded on human chromosome 22 (CHC22) displays distinct biochemistry, distribution and function compared with… Expand
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Highly Cited
2000
Highly Cited
2000
Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like).
Anaplastic lymphoma kinase (ALK)-positive lymphomas are characterized by expression of a hybrid protein, comprising the… Expand
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1997
1997
Disruption of the clathrin heavy chain-like gene (CLTCL) associated with features of DGS/VCFS: a balanced (21;22)(p12;q11) translocation.
The smallest region of deletion overlap in the patients we have studied defines a DIGeorge syndrome/velocardiofacial syndrome… Expand
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