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CLTCL1 wt Allele

Known as: Clathrin, Heavy Polypeptide D Gene, CHC17, FLJ36032 
Human CLTCL1 wild-type allele is located in the vicinity of 22q11.2 and is approximately 112 kb in length. This allele, which encodes clathrin heavy… 
National Institutes of Health

Related topics

Related topics

4 relations
CLTC geneCLTC wt AlleleReceptor Mediated Endocytosis

Broader (1)

CLTCL1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development
Congenital inability to feel pain is rare, but the identification of causative genes is translating into the development of novel… 
Highly Cited
2012
Highly Cited
2012
Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
Clathrin inactivation during S phase destabilizes the microtubule-binding protein ch-TOG, affecting its centrosomal localization… 
Highly Cited
2010
Highly Cited
2010
The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step
CHC22 is needed for retrograde trafficking from endosomes to the trans-Golgi, unlike its clathrin sibling CHC17, and in a manner… 
Highly Cited
2009
Highly Cited
2009
A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism
GLUT4, Clathrin, and Glucose In human muscle, the GLUT4 glucose transport pathway responds to insulin and is responsible for 70… 
Highly Cited
2005
Highly Cited
2005
Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution.
In humans, there are two isoforms each of clathrin heavy chain (CHC17 and CHC22) and light chain (LCa and LCb) subunits, all… 
2004
2004
Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.
The muscle isoform of clathrin heavy chain, CHC22, has 85% sequence identity to the ubiquitously expressed CHC17, yet its… 
Highly Cited
2001
Highly Cited
2001
A novel clathrin homolog that co‐distributes with cytoskeletal components functions in the trans‐Golgi network
A clathrin homolog encoded on human chromosome 22 (CHC22) displays distinct biochemistry, distribution and function compared with… 
2001
2001
FM1-43 Imaging Reveals cGMP-Dependent Long-Term Depression of Presynaptic Transmitter Release
A persistent question concerning mechanisms underlying long-term, activity-dependent synaptic plasticity is whether the sites of… 
Highly Cited
2000
Highly Cited
2000
Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like).
Anaplastic lymphoma kinase (ALK)-positive lymphomas are characterized by expression of a hybrid protein, comprising the… 
1997
1997
Disruption of the clathrin heavy chain-like gene (CLTCL) associated with features of DGS/VCFS: a balanced (21;22)(p12;q11) translocation.
The smallest region of deletion overlap in the patients we have studied defines a DIGeorge syndrome/velocardiofacial syndrome… 
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