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CLEC14A gene

Known as: C-TYPE LECTIN DOMAIN FAMILY 14, MEMBER A, C-type lectin domain family 14 member A, CLEC14A 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Genes

Papers overview

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2018
2018
Exploring the therapeutic potential of CAR-engineered T-cells targeting endothelial markers on tumour and inflamed vasculature
T-cells engineered to target tumour antigens through surface-expressed chimeric antigen receptors (CARs) are highly effective in… 
2017
2017
04.07 Microrna-146a controls local bone destruction by regulating fibroblast induced osteoclastogenesis in inflammatory arthritis
Background MicroRNA (MiR-) 146a plays an important role in the regulation of the innate immune response and has also been shown… 
2016
2016
Investigating the intracellular interactions of CLEC14A and the characterisation of monoclonal antibodies targeting CLEC14A
CLEC14A is a tumour endothelial marker known to regulate sprouting angiogenesis. While the extracellular interactions of CLEC14A… 
2016
2016
Abstract 3330: Tumor angiogenesis and cancer stem cells in serous adenocarcinoma of the ovary
Angiogenesis is required for tumor growth and metastasis. The conventional view of tumour angiogenesis is that tumours get their… 
2016
2016
Soluble expression of disulfide-bonded C-type lectin like domain of human CD93 in the cytoplasm of Escherichia coli.
2014
2014
Abstract LB-256: Immunotherapy using genetically modified T lymphocytes to target CLEC14A on the tumor vasculature
Chimeric antigen receptor (CAR) therapy combines the specificity of a monoclonal antibody with the potent cytotoxic and immune… 
2013
2013
Validation and identification of tumour endothelial markers and their uses in cancer vaccine
The abnormal tumour microenvironment, which is typically hypoxic, acidic and with poor blood flow, induces the endothelial… 
2012
2012
Investigating the interaction between the tetraspanin CD82 and gangliosides, and, The binding partners of CLEC14A and the function of the CLEC14A extracellular domain
Project 1: CD82 is a tetraspanin involved in tumour metastasis suppression. It is downregulated in several cancers including… 
2012
2012
Identifying binding partners of CLEC14A and Molecular studies of NKG2D-ULBP interactions
Blood vessels associated with tumours express a whole range of different protein tumour endothelial markers (TEMs) compared to… 
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