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CHOP-ATF4 complex

Known as: CHOP-CREB-2 complex, GADD153-ATF4 complex, GADD153-ATF4 complex location 
A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas
Malignant gliomas are devastating neoplasia with limited curative treatment options. Temozolomide (TMZ, Temcat®, Temodal® or… 
Review
2016
Review
2016
CHOP-like-14 compared to CHOP-like-21 for patients with aggressive lymphoma – a meta-analysis of randomized controlled trials
Background. R-CHOP-21 has remained the standard chemotherapy for aggressive non-Hodgkin's lymphoma. It was suggested that… 
2015
2015
Laminar inflammatory events in lean and obese ponies subjected to high carbohydrate feeding: Implications for pasture-associated laminitis.
REASONS FOR PERFORMING STUDY Acute, massive enteral carbohydrate overload is associated with laminar inflammation in equids; it… 
2007
2007
Myxoid Liposarcoma With Cartilaginous Differentiation: Identification of the Same Type II TLS-CHOP Fusion Gene Transcript in Both Lipogenic and Chondroid Components
Heterologous differentiation in adipocytic tumors is a rare phenomenon. Only 4 cases of myxoid liposarcoma (MLS) with… 
2002
2002
Temperature-dependent localization of TLS-CHOP to splicing factor compartments.
The myxoid/round cell liposarcoma oncogene TLS-CHOP belongs to a growing family of tumor type specific fusion genes generated by… 
2002
2002
Insights into the Schrock 'chop-chop' reaction gained from density functional theory and preparation and structure of W2(mu-PhCCPh)(SC6H4-2-Me)6.
Computations employing density functional theory on the reactions between ethyne and the model compounds (HE)3M identical to M(EH… 
2002
2002
Phaco one‐chop nucleotomy
2000
2000
Randomized Comparison of Mobilization Kinetics of Circulating CD34+ Cells Between Biweekly CHOP and Dose-Escalated CHOP with the Prophylactic Use of Lenograstim (Glycosylated rHuG-CSF) in Aggressive…
High-dose chemotherapy with autologous hematopoietic stem cell transplantation has been expected to result in a promising outcome… 
1999
1999
Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary
1998
1998
Alternating triple therapy for the treatment of intermediate grade and immunoblastic lymphoma.
BACKGROUND CHOP is currently considered the gold standard of treatment for intermediate grade lymphomas. We designed a new… 
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